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Product Info Summary
| SKU: | A08907 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, WB |
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Product info
Product Name
Anti-CLIP170 Antibody
SKU/Catalog Number
A08907
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-CLIP170 Antibody (Catalog # A08907). Tested in ELISA, WB, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
CLIP170 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-CLIP170 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08907)
Host
Rabbit
Contents
CLIP170 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
CLIP170 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human CLIP170. The immunogen is located within amino acids 1340 - 1390 of CLIP170.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
CUEDC2 antibody will not cross-react with CUEDC1.
Reactive Species
A08907 is reactive to CLIP1 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
162246 MW
Background of CLIP170
CLIP170 was initially identified as a new type of intermediate filament associated protein that is highly expressed in Reed-Sternberg cells, the tumoral cells diagnostic for Hodgkin's disease. Later experiments showed that it is located at microtubule plus ends and is required for the binding of endocytic carrier vesicles. CLIP170 has also been suggested to act with LIS1, a protein implicated in brain development, to regulate dynein/dynactin binding microtubules. Other studies suggest that CLIP170 can influence the formation of lamellipodia and cell invasion by invasive breast cancer cells by regulating the release of kinesin and IQGAP1 from a complex of those proteins, CLIP170 and Rac1. At least two isoforms of CLIP170 are known to exist.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A08907 is guaranteed for ELISA, IF, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CLIP170 antibody can be used for detection of CLIP170 by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunoflourescence starting at 20 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of CLIP170 in rat brain tissue lysate with CLIP170 antibody at (A) 0.5 and (B) 1 μg/mL.
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Immunofuorescence of CLIP170 in human brain tissue with CLIP170 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For CLIP1 (Source: Uniprot.org, NCBI)
Gene Name
CLIP1
Full Name
CAP-Gly domain-containing linker protein 1
Weight
162246 MW
Alternative Names
RSN, CLIP, CYLN1, CLIP170, CLIP-170, RSN, CAP-Gly domain-containing linker protein 1, Cytoplasmic linker protein 1 CLIP1 CLIP, CLIP-17070, CYLN1, RSN, CLIP1 CAP-Gly domain containing linker protein 1 CAP-Gly domain-containing linker protein 1|cytoplasmic linker protein 1|cytoplasmic linker protein 170 alpha-2|cytoplasmic linker protein CLIP-170|restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CLIP1, check out the CLIP1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CLIP1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CLIP170 Antibody (A08907)
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