Anti-CIDE-A Antibody

Product Name

Anti-CIDE-A Antibody

View all CIDEA Antibodies

SKU/Catalog Number

A02671-1

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-CIDE-A Antibody (Catalog # A02671-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse.

Storage & Handling

CIDE-A antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.

Cite This Product

Anti-CIDE-A Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02671-1)

Host

Rabbit

Contents

CIDE-A Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

CIDE-A antibody was raised against an 18 amino acid peptide near the carboxy terminus of mouse CIDE-A. The immunogen is located within the last 50 amino acids of CIDE-A.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

It has no cross activity to CIDE-B.

Reactive Species

A02671-1 is reactive to CIDEA in Human, Mouse

Reconstitution

Observed Molecular Weight

68 kDa

Calculated molecular weight

24687 MW

Background of CIDEA

Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified. CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE-A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45. CIDE-A is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation. CIDE-A is expressed in many tissues.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A02671-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

CIDE-A antibody can be used for detection of CIDE-A by Western blot at 0.5 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human and mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

Gene/Protein Information For CIDEA (Source: Uniprot.org, NCBI)

Alternative Names

CIDE-A, Cell death activator CIDE-A, Cell death-inducing DFFA-like effector A CIDEA CIDE-A cell death inducing DFFA like effector a cell death activator CIDE-A

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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