Anti-Centrosomal protein of 152 kDa CEP152 Antibody

Product Name

Anti-Centrosomal protein of 152 kDa CEP152 Antibody

View all CEP152 Antibodies

SKU/Catalog Number

A05246

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-Centrosomal protein of 152 kDa CEP152 Antibody (Catalog # A05246). Tested in IHC applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Centrosomal protein of 152 kDa CEP152 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05246)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human CEP152.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A05246 is reactive to CEP152 in Human, Mouse

Reconstitution

Observed Molecular Weight

111 kDa

Calculated molecular weight

195626 MW

Background of CEP152

Necessary for centrosome duplication. Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation. Also plays a key role in deuterosome-mediated centriole amplification in multiciliated that can generate more than 100 centrioles. Overexpression of CEP152 can drive amplification of centrioles.

Nagase T., DNA Res. 5:355-364(1998).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Andersen J.S., Nature 426:570-574(2003).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A05246 is guaranteed for IHC Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry: 1:50~1:100

Validation Images & Assay Conditions

Gene/Protein Information For CEP152 (Source: Uniprot.org, NCBI)

Alternative Names

Centrosomal protein of 152 kDa;Cep152;CEP152;KIAA0912; CEP152 MCPH4, MCPH9, SCKL5 centrosomal protein 152 centrosomal protein of 152 kDa|asterless|centrosomal protein 152kDa|microcephaly, primary autosomal recessive 4

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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