CEP152 Antibodies

AND CEP152 ELISA kits, CEP152 Proteins

Many biological assays use antibodies to detect CEP152, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CEP152 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CEP152 antibodies...

We validate the specificity of these antibodies to CEP152 by testing them on tissues known to express CEP152 positively and negatively. Browse below to find the CEP152 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CEP152 Infographic by Boster Bio

All CEP152 Products

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Specificity

Applications

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Anti-Centrosomal protein of 152 kDa CEP152 Antibody

5 Q&As

Human, Mouse

IHC

$360
Cat # A05246
100 µl

Anti-CEP152 Antibody

1 Q&As

Human, Mouse

ELISA, IHC-P, WB, IF (paraffin)

$335
Cat # A30605
100ul

Anti-Centrosomal protein of 152 kDa CEP152 Antibody

Human, Mouse

ELISA, IHC, WB

$380
Cat # A05246-1
100ul

CEP152 Overview

Facts about Centrosomal protein of 152 kDa.

CEP152 3D structure. Source: alphafold

Centrosomal protein of 152 kDa (CEP152)

Necessary for centrosome duplication; the purpose seems also to involve CEP63, CDK5RAP2 and WDR62 via a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (PubMed:26297806). Acts as a molecular scaffold facilitating the interaction of PLK4 and CENPJ, 2 molecules involved in centriole formation (PubMed:21059844, PubMed:20852615).

Proposed to snatch PLK4 from PLK4:CEP92 complexes in early G1 daughter centriole and to reposition PLK4 in the outer boundary of a newly forming CEP152 ring structure (PubMed:24997597). Also plays an integral role in deuterosome-mediated centriole amplification in multiciliated that could generate over 100 centrioles (By similarity).

Gene Information

Human
Gene Name:	CEP152
Uniprot:	O94986
Entrez:	22995

Family

Belongs to:

CEP152 family

Alternative Names

centrosomal protein 152kDa; centrosomal protein of 152 kDa; Cep152; FLJ21594; KIAA0912MCPH4

Molecular Weight

Mass (kDA):
195.626 kDA

Genomic Context


Human

Location:	15q21.1
Sequence:	15; NC_000015.10 (48662534..48811904, complement)

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Colocalizes with CDK5RAP2, WDR62 and CEP63 in a discrete ring around the proximal end of the parental centriole. At this site, a cohesive structure is predicted to engage parental centrioles and procentrioles (PubMed:21983783, PubMed:26297806). Localizes to the deuterosome (By similarity). Localizes to pericentriolar material (PCM) (PubMed:26337392).