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Product Info Summary
| SKU: | MA1022 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | IHC, ICC, WB |
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Product info
Product Name
Anti-Cdk7/CAK Antibody (Monoclonal, MO-1.1)
SKU/Catalog Number
MA1022
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-Cdk7/CAK Antibody (Monoclonal, MO-1.1) catalog # MA1022. Tested in IHC, ICC, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Cdk7/CAK Antibody (Monoclonal, MO-1.1) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1022)
Host
Mouse
Contents
Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Clonality
Monoclonal
Clone Number
MO-1.1
Isotype
Mouse IgG2b
Immunogen
Recombinant human Cdk7 protein.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
MA1022 is reactive to Cdk7 in Human
Reconstitution
Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Observed Molecular Weight
37 kDa
Calculated molecular weight
37141 MW
Background of CDK7
CDK-activating kinases (CAKs) are multisubunit proteins that phosphorylate and thus activate certain cyclin-dependent protein kinases in the regulation of cell cycle progression. Cyclin dependent kinase7 (CDK7) gene is mapped to chromosome 2p15-cen. CDK7 functions in both cyclin binding and T-loop phosphorylation and that these 2 steps of CDK1 activation are mutually dependent.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
MA1022 is guaranteed for IHC, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunocytochemistry , 1μg/ml, Human, -
Immunohistochemistry (Frozen Section), 0.5μg/ml, Human, -
Western blot, 0.25μg/ml, Human
Positive Control
IHC: Human Breast Tissue
Validation Images & Assay Conditions
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Anti-Cdk7/CAK antibody (monoclonal), MA1022, IHC(P)
IHC(P): Human Breast Tissue
Protein Target Info & Infographic
Gene/Protein Information For Cdk7 (Source: Uniprot.org, NCBI)
Gene Name
Cdk7
Full Name
Cyclin-dependent kinase 7
Weight
37141 MW
Superfamily
protein kinase superfamily
Alternative Names
Cyclin-dependent kinase 7;2.7.11.22;2.7.11.23;39 protein kinase;P39 Mo15;CDK-activating kinase 1;Cell division protein kinase 7;TFIIH basal transcription factor complex kinase subunit;Cdk7;Cak, Cak1, Mo15; CDK7 CAK, CAK1, CDKN7, HCAK, MO15, STK1, p39MO15 cyclin dependent kinase 7 cyclin-dependent kinase 7|39 KDa protein kinase|CDK-activating kinase 1|TFIIH basal transcription factor complex kinase subunit|cell division protein kinase 7|cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)|homolog of Xenopus MO15 Cdk-activating kinase|kinase subunit of CAK|serine/threonine kinase stk1|serine/threonine protein kinase 1|serine/threonine protein kinase MO15
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Cdk7, check out the Cdk7 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Cdk7: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Cdk7/CAK Antibody (Monoclonal, MO-1.1) (MA1022)
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