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Product Info Summary
| SKU: | PA2126-2 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-Cyclin-dependent kinase 7 Cdk7 Antibody Picoband®
SKU/Catalog Number
PA2126-2
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-Cyclin-dependent kinase 7 Cdk7 Antibody catalog # PA2126-2. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Cyclin-dependent kinase 7 Cdk7 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA2126-2)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of mouse Cdk7, identical to the related rat sequence, and different from the related human sequence by two amino acids.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA2126-2 is reactive to Cdk7 in Human, Mouse, Rat
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Observed Molecular Weight
39 kDa
Calculated molecular weight
38968 MW
Background of CDK7
Cyclin-dependent kinase 7, also known as cell division protein kinase 7, is an enzyme that in humans is encoded by the CDK7 gene. The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. The gene was assigned to human chromosome 5q13.2. Serine/threonine kinase involved in cell cycle control and in RNA polymerase II-mediated RNA transcription. CDK7 is the catalytic subunit of the CDK-activating kinase (CAK) complex. It is required for DNA-bound peptides-mediated transcription and cellular growth inhibition.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
PA2126-2 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse
Positive Control
WB: Rat Testis Tissue, Rat Ovary Tissue, HELA Whole Cell, MCF-7 Whole Cell, A549 Whole Cell, COLO320 Whole Cell
Validation Images & Assay Conditions
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Anti-Cdk7 antibody, PA2126-2, Western blotting
All lanes: Anti Cdk7 (PA2126-2) at 0.5ug/ml
Lane 1: Rat Testis Tissue Lysate at 50ug
Lane 2: Rat Ovary Tissue Lysate at 50ug
Lane 3: HELA Whole Cell Lysate at 40ug
Lane 4: MCF-7 Whole Cell Lysate at 40ug
Lane 5: A549 Whole Cell Lysate at 40ug
Lane 6: COLO320 Whole Cell Lysate at 40ug
Predicted bind size: 39KD
Observed bind size: 39KD
Protein Target Info & Infographic
Gene/Protein Information For Cdk7 (Source: Uniprot.org, NCBI)
Gene Name
Cdk7
Full Name
Cyclin-dependent kinase 7
Weight
38968 MW
Superfamily
protein kinase superfamily
Alternative Names
Cyclin-dependent kinase 7;2.7.11.22;2.7.11.23;39 kDa protein kinase;P39 Mo15;CDK-activating kinase;CR4 protein kinase;CRK4;Cell division protein kinase 7;Protein-tyrosine kinase MPK-7;TFIIH basal transcription factor complex kinase subunit;Cdk7;Cak, Cdkn7, Crk4, Mo15, Mpk-7; CDK7 CAK, CAK1, CDKN7, HCAK, MO15, STK1, p39MO15 cyclin dependent kinase 7 cyclin-dependent kinase 7|39 KDa protein kinase|CDK-activating kinase 1|TFIIH basal transcription factor complex kinase subunit|cell division protein kinase 7|cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)|homolog of Xenopus MO15 Cdk-activating kinase|kinase subunit of CAK|serine/threonine kinase stk1|serine/threonine protein kinase 1|serine/threonine protein kinase MO15
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Cdk7, check out the Cdk7 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Cdk7: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Cyclin-dependent kinase 7 Cdk7 Antibody Picoband® (PA2126-2)
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