Anti-CD158k Antibody

Product Name

Anti-CD158k Antibody

View all KIR3DL2/CD158k Antibodies

SKU/Catalog Number

A03677

Size

100μl

Form

Liquid

Description

Boster Bio Anti-CD158k Antibody catalog # A03677. Tested in IHC applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CD158k Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03677)

Host

Rabbit

Contents

PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthetic peptide from human protein at AA range: 221-270.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A03677 is reactive to KIR3DL2 in Human

Applications

A03677 is guaranteed for IHC Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

50230 MW

Background of KIR3DL2/CD158k

CAND1 is also known as TIP120A, and TATA-binding protein-interacting protein 120A. The SCF complex consists of the invariable components Skp1, Cul1, and Rbx1 as well as a variable F-box protein, and functions as an E3 ubiquitin ligase. E3 ubiquitin ligases regulate various physiological processes. CAND1 binds to Cul1 and potentially regulates the SCF complex. CAND1 physically associates with Cul1 in the nucleus and this interaction is mediated by a central region of Cul1 distinct from its binding sites for Skp1 and Rbx1. CAND1 selectively binds to unneddylated CUL1 and is dissociated by CUL1 neddylation. CAND1 forms a ternary complex with CUL1 and ROC1.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

IHC-P, 1:50-300

Validation Images & Assay Conditions

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Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200.

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Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200.

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Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200.

Gene/Protein Information For KIR3DL2 (Source: Uniprot.org, NCBI)

Alternative Names

killer cell immunoglobulin-like receptor 3DL2; CD158k; CL-5; killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2; KIR3DL2; NKAT4; NKAT-4; NKAT4A; NKAT4B; p140 KIR3DL2 3DL2, CD158K, KIR-3DL2, NKAT-4, NKAT4, NKAT4B, p140 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2 killer cell immunoglobulin-like receptor 3DL2|CD158 antigen-like family member K|KIR antigen 3DL2|MHC class I NK cell receptor|killer Ig receptor|killer cell immunoglobulin-like receptor 2DL2|killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2|killer-cell immunoglobulin-like receptor|natural killer-associated transcript 4|p70 NK receptor CL-5|p70 killer cell inhibitory receptor|p70 natural killer cell receptor clone CL-5

For more info on KIR3DL2, check out the KIR3DL2 Infographic

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In this infographic, you will see the following information for KIR3DL2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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