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Product Info Summary
| SKU: | PA1379 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Mouse |
| Host: | Rabbit |
| Application: | WB |
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Product info
Product Name
Anti-Macrophage Inflammatory Protein 1 beta/CCL4 Antibody Picoband®
View all CCL4/MIP-1 beta Antibodies
SKU/Catalog Number
PA1379
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-Macrophage Inflammatory Protein 1 beta/CCL4 Antibody catalog # PA1379. Tested in WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Macrophage Inflammatory Protein 1 beta/CCL4 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1379)
Host
Rabbit
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of mouse CCL4.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
PA1379 is reactive to Ccl4 in Mouse
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Observed Molecular Weight
90 kDa
Calculated molecular weight
10168 MW
Background of CCL4/MIP-1 beta
Chemokine (C-C motif) ligand 4, also known as CCL4, is a protein which in humans is encoded by the CCL4 gene. It is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize MIP-1-beta. Modi et al. (1991) assigned the SCYA4 gene to a slightly more distal location than had Irving et al. (1990): 17q21-q23 rather than 17q11-q21.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
PA1379 is guaranteed for WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 0.1-0.5μg/ml, Mouse
Positive Control
WB: Mouse Spleen Tissue, Mouse Cardiac Muscle Tissue, Mouse Lung Tissue, Mouse Kidney Tissue, Mouse Skeletal Muscle Tissue
Validation Images & Assay Conditions
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All lanes: Anti-CCL4, PA1379
Lane 1: Mouse Spleen Tissue Lysate
Lane 2: Mouse Cardiac Muscle Tissue Lysate
Lane 3: Mouse Lung Tissue Lysate
Lane 4: Mouse Kidney Tissue Lysate
Lane 5: Mouse Skeletal Muscle Tissue Lysate
Protein Target Info & Infographic
Gene/Protein Information For Ccl4 (Source: Uniprot.org, NCBI)
Gene Name
Ccl4
Full Name
C-C motif chemokine 4
Weight
10168 MW
Superfamily
intercrine beta (chemokine CC) family
Alternative Names
C-C motif chemokine 4;Immune activation protein 2;ACT-2;ACT2;Macrophage inflammatory protein 1-beta;MIP-1-beta;Protein H400;SIS-gamma;Small-inducible cytokine A4;Ccl4;Mip1b, Scya4; CCL4 ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4 C-C motif chemokine ligand 4 C-C motif chemokine 4|G-26 T-lymphocyte-secreted protein|MIP-1-beta(1-69)|PAT 744|SIS-gamma|T-cell activation protein 2|chemokine (C-C motif) ligand 4|lymphocyte activation gene 1 protein|macrophage inflammatory protein 1-beta|secreted protein G-26|small inducible cytokine A4 (homologous to mouse Mip-1b)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on Ccl4, check out the Ccl4 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for Ccl4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Macrophage Inflammatory Protein 1 beta/CCL4 Antibody Picoband® (PA1379)
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