This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
3 Citations 8 Q&As
3 Citations 10 Q&As
Facts about C-C motif chemokine 4.
One of the Significant HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
Human | |
---|---|
Gene Name: | CCL4 |
Uniprot: | P13236 |
Entrez: | 6351 |
Belongs to: |
---|
intercrine beta (chemokine CC) family |
ACT2; ACT-2; AT744.1; C-C motif chemokine 4; CCL4; chemokine (C-C motif) ligand 4; Exodus-3; G-26 T-lymphocyte-secreted protein; G-26; HC21; LAG1; LAG-1; Lymphocyte activation gene 1 protein; Macrophage inflammatory protein 1-beta; MIP1 beta; MIP-1 beta; MIP1B; MIP1B1; MIP-1-beta; MIP-1-beta(1-69); PAT 744; Protein H400; SCYA2; SCYA4; secreted protein G-26; SIS-gamma; small inducible cytokine A4 (homologous to mouse Mip-1b); Small-inducible cytokine A4; T-cell activation protein 2
Mass (kDA):
10.212 kDA
Human | |
---|---|
Location: | 17q12 |
Sequence: | 17; NC_000017.11 (36103827..36105614) |
Secreted.
PMID: 2462251 by Lipes M.A., et al. Identification, cloning, and characterization of an immune activation gene.
PMID: 2521882 by Zipfel P.F., et al. Mitogenic activation of human T cells induces two closely related genes which share structural similarities with a new family of secreted factors.
*More publications can be found for each product on its corresponding product page