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Key=sku, value=PB9854
Key=has_options, value=1
Key=required_options, value=1
Key=created_at, value=2016-02-26 09:06:26
Key=updated_at, value=2024-10-04 05:03:22
Key=mst_search_weight, value=0
Key=status, value=Enabled
Key=name, value=Anti-Cathepsin D/CTSD Antibody Picoband®
Key=cj_search_index
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Key=is_recurring, value=No
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Key=template, value=antibodies
Key=host, value=Rabbit
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Key=yoast_keyword_score, value=68
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Key=badge, value=free-antibody-validation
Key=price, value=370.0000
Key=weight, value=1.0000
Key=meta_title, value=Anti-Cathepsin D/CTSD Antibody Picoband® PB9854 | Boster Bio
Key=meta_description, value=Rabbit polyclonal Cathepsin D Antibody [PB9854] that detects human cathepsin D by Flow Cyt, IF, IHC, ICC & WB. Tested in humans, 1 citation.
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Key=url_key, value=anti-cathepsin-d-picoband-trade-antibody-pb9854-boster
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Key=gift_message_available, value=No
Key=size, value=100 μg/vial
Key=protein_name, value=Cathepsin D
Key=gene_full_name, value=Cathepsin D
Key=uniprot_id, value=P07339
Key=reconstitution, value=Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Key=sensitivity
Key=applications, value=Flow Cytometry, IF, IHC, ICC, WB
Key=reactivity, value=Human
Key=form, value=Lyophilized
Key=concentration, value=Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Key=cross_reactivity, value=No cross-reactivity with other proteins.
Key=recommended_detection_systems, value=Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P) and ICC.
Key=predicted_reactivity
Key=source_company, value=Boster PB9854
Key=isotype, value=Rabbit IgG
Key=molecular_weight, value=44552 MW
Key=sample_size_available, value=30ug for $99, contact us for details
Key=related_product_skus, value=B0001-5,AR1156,AR0146
Key=product_category, value=Primary Antibodies
Key=research_category, value=Cancer, Cell Adhesion Proteins, Cell Biology, Cytoskeleton/ECM, ECM Enzymes, Extracellular Matrix, Invasion/Microenvironment, Membrane Proteins, Neuroscience, Proteolysis/Ubiquitin, Proteolytic Enzymes, Signal Transduction
Key=clonality, value=Polyclonal
Key=swatch_image, value=/e/k/ek0673_3.png
Key=rating_value, value=96.4
Key=review_count, value=4
Key=phospho_site
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Key=yoast_focus_keyword, value=Cathepsin D/CTSD Antibody
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Key=cj_related_products, value=Neuronal Ceroid-lipofuscinoses:MA1013|A01361|FEK0672|PROTP07339|PB9781
Key=description, value=Boster Bio Anti-Cathepsin D/CTSD Antibody Picoband® catalog # PB9854. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=short_description, value=Boster Bio Anti-Cathepsin D/CTSD Antibody Picoband® catalog # PB9854. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=meta_keyword, value=Cathepsin D/CTSD Antibody
Key=contents, value=Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Key=background, value=Cathepsin D is a protein that in humans is encoded by the CTSD gene. This proteinase is a member of the peptidase C1 family, having a specificity similar to but narrower than that of pepsin A. It is mapped to 11p15.5. The cDNA encodes a 412-amino acid protein with 20 and 44 amino acids in a pre- and prosegment, respectively. Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease and it has been considered as a breast cancer tumor marker.
Key=gene_name, value=CTSD
Key=synonyms, value=Cathepsin D;3.4.23.5;Cathepsin D light chain;Cathepsin D heavy chain;CTSD;CPSD;
Key=application_details, value=Western blot, 0.1-0.5μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Immunocytochemistry/Immunofluorescence, 2μg/ml, Human
Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Human
Key=subcellular_localization, value= Lysosome. Melanosome. Secreted, extracellular space. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380). .
Key=tissue_specificity, value= Expressed in the aorta extrcellular space (at protein level). .
Key=protein_function, value= Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Key=application_notes, value=Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
Key=competitor_equivalent_skus, value=sc 10725|sc 13148|sc 136282|sc 374381|sc 377124|sc 377299|sc 53927|sc 6486|sc 6487|sc 6487 R|sc 6488|sc 6494
Key=immunogen, value=E.coli-derived human Cathepsin D recombinant protein (Position: M201-L412). Human Cathepsin D shares 84.4% and 84% amino acid (aa) sequence identity with mouse and rat Cathepsin D, respectively.
Key=purification, value=Immunogen affinity purified.
Key=storage, value=Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Key=custom_attribute_1, value=28, 45 kDa
Key=custom_attribute_2, value=WB: human HepG2 whole cell, human A431 whole cell, human MCF-7 whole cell, human Jurkat whole cell
IHC: human intestinal cancer tissue
ICC/IF: MCF-7 cell
FCM: SiHa cell
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