Anti-cardiac Troponin C/TNNC1 Antibody Picoband®

Product Name

Anti-cardiac Troponin C/TNNC1 Antibody Picoband®

View all Troponin C (cardiac) Antibodies

SKU/Catalog Number

PA1779

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-cardiac Troponin C/TNNC1 Antibody catalog # PA1779. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-cardiac Troponin C/TNNC1 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1779)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human cardiac Troponin C, identical to the related rat and mouse sequences .

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1779 is reactive to TNNC1 in Human, Mouse, Rat

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

18 kDa

Calculated molecular weight

18403 MW

Background of Troponin C (cardiac)

Troponin C1 (TNNC1) (troponin C type 1 (slow)), also called TROPONIN C, SLOW-TWITCH SKELETAL MUSCLE or TNC, is a protein that in humans is encoded by the TNNC1 gene. Using a "monochromosomal" hybrid panel, the TNNC1 gene is mapped to chromosome 3; subsequent analysis of the Genebridge 4 radiation hybrid panel localized the gene to 3p in a region consistent with the earlier assignment. Circular dichroism measurements revealed changes in the secondary structures of the TNNC1 mutants A8V, C84Y, and D145E.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

PA1779 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Rat, Human, Mouse

Positive Control

WB: Rat Skeletal Muscle Tissue
IHC: Rat Cardiac Muscle Tissue

Validation Images & Assay Conditions

Gene/Protein Information For TNNC1 (Source: Uniprot.org, NCBI)

Alternative Names

Troponin C, slow skeletal and cardiac muscles;TN-C;TNNC1;TNNC; TNNC1 CMD1Z, CMH13, TN-C, TNC, TNNC troponin C1, slow skeletal and cardiac type troponin C, slow skeletal and cardiac muscles|cardiac troponin C|slow twitch skeletal/cardiac muscle troponin C|troponin C type 1 (slow)

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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