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- Table of Contents
1 Citations 6 Q&As
Facts about Troponin C, slow skeletal and cardiac muscles.
The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. .
Human | |
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Gene Name: | TNNC1 |
Uniprot: | P63316 |
Entrez: | 7134 |
Belongs to: |
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troponin C family |
cardiac troponin C; CMD1Z; CMH13; slow twitch skeletal/cardiac muscle troponin C; TNC; TN-C; TNNC; troponin C type 1 (slow); troponin C, slow skeletal and cardiac muscles; troponin C, slow; troponin C1, slow
Mass (kDA):
18.403 kDA
Human | |
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Location: | 3p21.1 |
Sequence: | 3; NC_000003.12 (52451100..52454041, complement) |
This article will review the Boster Bio Anticardiac Troponin/TNNC1 Marker. We'll examine its applications and research. Boster scientists may submit their results to receive samples from other species or applications. The best thing is that it's open for all scientists worldwide. You can submit results to earn product credits.
This antibody has been validated against Troponin C, the Human protein. This protein is encoded at chromosome 3, by the TNNC1 genes. A Genebridge4 radiation-hybrid panel detected TNNC1 in chromosome3p. Circular dichroism measurements revealed a change in secondary structure in TNNC1 mutations. There are many formats for the antibody, including Western blot and IHC.
Cardiac troponins have the ability to detect myocardial injury. Although the concentration of cardiac troponins can be used to determine myocardial injury in quantitative terms, it does not reveal the underlying mechanism. The laboratory can diagnose acute myocardial damage (AMI) using the two cardioprotective biomarkers, cardiac troponins I and T. Both markers are sensitive and specific for myocardial injury. However, the process to degrade troponins is complicated.
PMID: 3951483 by Roher A., et al. The amino acid sequence of human cardiac troponin-C.
PMID: 3166492 by Gahlmann R., et al. Differential expression of slow and fast skeletal muscle troponin C. Slow skeletal muscle troponin C is expressed in human fibroblasts.
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