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Key=sku, value=A00654-1
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Key=created_at, value=2019-08-23 07:43:09
Key=updated_at, value=2024-09-26 01:02:28
Key=mst_search_weight, value=0
Key=status, value=Enabled
Key=name, value=Anti-c-Maf/MAF Antibody Picoband®
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Key=template, value=antibodies
Key=host, value=Rabbit
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Key=yoast_keyword_score, value=-1172
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Key=badge, value=free-antibody-validation
Key=price, value=370.0000
Key=weight, value=1.0000
Key=meta_title, value=Anti-c-Maf/MAF Antibody Picoband® | Bosterbio
Key=meta_description, value=Boster Bio Anti-c-Maf/MAF Antibody Picoband® catalog # A00654-1. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. Supplied as 100μg/vial in Lyophilized form antibody.
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Key=url_key, value=anti-c-maf-maf-picoband-trade-antibody-a00654-1-boster
Key=url_path, value=anti-c-maf-maf-picoband-trade-antibody-a00654-1-boster
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Key=image_label, value=Figure 7. Flow Cytometry analysis of HepG2 cells using anti-MAF antibody (A00654-1).
Overlay histogram showing HepG2 cells stained with A00654-1 (Blue line). To facilitate intracellular staining, cells were fixed with 4% paraformaldehyde and permeabi
Key=small_image_label, value=Figure 7. Flow Cytometry analysis of HepG2 cells using anti-MAF antibody (A00654-1).
Overlay histogram showing HepG2 cells stained with A00654-1 (Blue line). To facilitate intracellular staining, cells were fixed with 4% paraformaldehyde and permeabi
Key=thumbnail_label, value=Figure 7. Flow Cytometry analysis of HepG2 cells using anti-MAF antibody (A00654-1).
Overlay histogram showing HepG2 cells stained with A00654-1 (Blue line). To facilitate intracellular staining, cells were fixed with 4% paraformaldehyde and permeabi
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Key=size, value=100 μg/vial
Key=gene_full_name, value=MAF bZIP transcription factor
Key=uniprot_id, value=O75444
Key=reconstitution, value=Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Key=applications, value=Flow Cytometry, IHC, WB
Key=reactivity, value=Human, Mouse, Rat
Key=form, value=Lyophilized
Key=concentration, value=Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Key=cross_reactivity, value=No cross-reactivity with other proteins.
Key=recommended_detection_systems, value="Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal d
Key=source_company, value=Boster A00654-1
Key=isotype, value=Rabbit IgG
Key=molecular_weight, value=42187 MW
Key=sample_size_available, value=30ug for $99, contact us for details
Key=related_product_skus, value=B0001-5,AR1156,AR0146
Key=product_category, value=Primary Antibodies
Key=research_category, value=Adaptive Immunity, Cardiovascular, Hematopoietic Progenitors, Immunology, Lymphoid, Myeloid, Stem Cells, T Cells, T Lymphocytic Lineage
Key=clonality, value=Polyclonal
Key=swatch_image, value=/a/0/a00651-5-il1rn-primary-antibodies-wb-testing-1.jpg
Key=rating_value, value=100
Key=review_count, value=4
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Key=cj_related_products, value=Delayed Hypersensitivity:PB9681|A04548|EZ0802^Fibrosarcoma:A00348|PROTP31240^Lens Fiber Cell Differentiation:PB9634
Key=description, value=Boster Bio Anti-c-Maf/MAF Antibody Picoband® catalog # A00654-1. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=short_description, value=Boster Bio Anti-c-Maf/MAF Antibody Picoband® catalog # A00654-1. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key=meta_keyword, value=Anti-c-Maf/MAF Antibody Picoband®
Key=contents, value=Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Key=background, value=Transcription factor Maf also known as proto-oncogene c-Maf or V-maf musculoaponeurotic fibrosarcoma oncogene homolog is a transcription factor that in humans is encoded by the MAF gene. It is mapped to 16q23.2. The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene.
Key=gene_name, value=MAF
Key=synonyms, value=Transcription factor Maf; Proto-oncogene c-Maf; V-maf musculoaponeurotic fibrosarcoma oncogene homolog; MAF
Key=application_details, value="Western blot, 0.25-0.5μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Human
"
Key=subcellular_localization, value= Membrane; Single-pass type I membrane protein.
Key=tissue_specificity, value=Expressed in endothelial cells.
Key=application_notes, value="Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users."
Key=competitor_equivalent_skus, value=sc 13505|sc 6946|sc 15331|sc 390756|sc 18918|sc 18851|sc 18905|sc 71476|sc 53087
Key=immunogen, value=A synthetic peptide corresponding to a sequence at the N-terminus of human c-Maf/MAF, identical to the related mouse and rat sequences.
Key=purification, value=Immunogen affinity purified.
Key=storage, value=Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Key=custom_attribute_1, value=42-50 kDa
Key=custom_attribute_2, value=WB: human HEK293 whole cell, human K562 whole cell, human U2OS whole cell, human placenta tissue, human Caco-2 whole cell, human PC-3 whole cell, human HepG2 whole cell, human THP-1 whole cell
IHC: human tonsil tissue, human mammary cancer tissue, human placenta tissue, rat lung tissue, mouse liver tissue
FCM: HepG2 cell
Key=protein_function, value=Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element. Activates transcription of the CD13 proximal promoter in endothelial cells. Represses transcription of the CD13 promoter in early stages of myelopoiesis by affecting the ETS1 and MYB cooperative interaction. Involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. Binds to the sequence 5'-[GT]G[GC]N[GT]NCTCAGNN-3' in the L7 promoter. Binds to the T-MARE (Maf response element) sites of lens-specific alpha- and beta-crystallin gene promoters. Binds element G1 on the glucagon promoter. Binds an AT-rich region adjacent to the TGC motif (atypical Maf response element) in the CD13 proximal promoter in endothelial cells (By similarity). When overexpressed, represses anti-oxidant response element (ARE)-mediated transcription. Involved either as an oncogene or as a tumor suppressor, depending on the cell context. Binds to the ARE sites of detoxifying enzyme gene promoters.
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