Anti-BIM(Ab-69) BCL2L11 Antibody

Product Name

Anti-BIM(Ab-69) BCL2L11 Antibody

View all BCL2L11 Antibodies

SKU/Catalog Number

A01552-1

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-BIM(Ab-69) BCL2L11 Antibody (Catalog # A01552-1). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-BIM(Ab-69) BCL2L11 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01552-1)

Host

Rabbit

Contents

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Peptide sequence around aa.67~71 (P-A-S-P-G) derived from Human BIM.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A01552-1 is reactive to BCL2L11 in Human, Mouse, Rat

Applications

A01552-1 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

22171 MW

Background of BCL2L11

Induces apoptosis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-a1, isoform Bim-a2 and isoform Bim-a3 induce apoptosis, although less potent than the isoforms BimEL, BimL and BimS. Isoform Bim-gamma induces apoptosis.

Fukazawa H, et al. (2004) Mol Cancer Ther ; 3(10): 1281-1288
Luciano F, et al. (2003) Oncogene ; 22(43): 6785-6793

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Predicted MW: 23kd
Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100

Validation Images & Assay Conditions

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Western blot analysis of extracts from Hela cells using BIM(Ab-69) antibody A01552-1.

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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using BIM(Ab-69) antibody A01552-1(left) or the same antibody preincubated with blocking peptide(right).

Gene/Protein Information For BCL2L11 (Source: Uniprot.org, NCBI)

Alternative Names

BAM; bcl-2 interacting mediator of cell death; bcl-2 interacting protein Bim; Bcl2-interacting mediator of cell death; bcl2-L-11; BCL2-like 11 (apoptosis facilitator); bcl-2-like protein 11; bcl-2-related ovarian death agonist; BIM-alpha6; BIM-beta6; BIM-beta7; BIMBOD; BimEL; BimL BCL2L11 BAM, BIM, BOD BCL2 like 11 bcl-2-like protein 11|BCL2-like 11 (apoptosis facilitator)|bcl-2 interacting mediator of cell death|bcl-2 interacting protein Bim|bcl-2-related ovarian death agonist

For more info on BCL2L11, check out the BCL2L11 Infographic

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In this infographic, you will see the following information for BCL2L11: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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