Anti-Bestrophin/BEST1 Antibody Picoband®

Bestrophin 1 antibody

Boster Bio Anti-Bestrophin/BEST1 Antibody Picoband® catalog # A01434-1. Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Info Summary

SKU: A01434-1
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: Flow Cytometry, IHC, ICC, WB

Product Name

Anti-Bestrophin/BEST1 Antibody Picoband®

View all Bestrophin 1 Antibodies

SKU/Catalog Number

A01434-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Bestrophin/BEST1 Antibody Picoband® catalog # A01434-1. Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Bestrophin/BEST1 Antibody Picoband® (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01434-1)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human Bestrophin, which shares 62.5% amino acid (aa) sequence identity with mouse Bestrophin.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A01434-1 is reactive to BEST1 in Human

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

68 kDa

Calculated molecular weight

51561 MW

Background of Bestrophin 1

Bestrophin-1 (Best1) is a protein that, in humans, is encoded by the BEST1 gene. This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A01434-1 is guaranteed for Flow Cytometry, IHC, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml
Immunohistochemistry (Frozen Section), 0.5-1μg/ml
Immunocytochemistry, 0.5-1μg/ml
Flow Cytometry (Fixed), 1-3μg/1x106 cells

Positive Control

WB: human A549 whole cell, human SGC-7901 whole cell, human U20S whole cell
FCM: Hela cell, LOVO cell

Validation Images & Assay Conditions

Gene/Protein Information For BEST1 (Source: Uniprot.org, NCBI)

Gene Name

BEST1

Full Name

Bestrophin-1

Weight

51561 MW

Superfamily

bestrophin family

Alternative Names

Bestrophin-1; TU15B; Vitelliform macular dystrophy protein 2; BEST1; VMD2 BEST1 ARB, BEST, BMD, Best1V1Delta2, RP50, TU15B, VMD2 bestrophin 1 bestrophin-1|Best disease|vitelliform macular dystrophy protein 2

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on BEST1, check out the BEST1 Infographic

BEST1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for BEST1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A01434-1

100μg

$370
A01434-1-10ug

10μg sample (liquid)

$99
A01434-1-Biotin

100 μg Biotin conjugated

$570
A01434-1-Cy3

100 μg Cy3 conjugated

$570
A01434-1-Dylight488

100 μg Dylight488 conjugated

$570
A01434-1-Dylight550

100 μg Dylight550 conjugated

$570
A01434-1-Dylight594

100 μg Dylight594 conjugated

$570
A01434-1-FITC

100 μg FITC conjugated

$570
A01434-1-HRP

100 μg HRP conjugated

$570
A01434-1-APC

100 μg APC conjugated

$670
A01434-1-PE

100 μg PE conjugated

$670
A01434-1-iFluor647

100 μg iFluor647 conjugated

$670
A01434-1-carrier-free

Carrier Free

$370
Rainbow Button View conjugates

Free Secondary Antibody

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A01434-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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