Anti-B3GALNT1 Antibody

Product Name

Anti-B3GALNT1 Antibody

View all B3GALNT1 Antibodies

SKU/Catalog Number

A09960

Size

100ul

Form

Liquid

Description

Boster Bio Anti-B3GALNT1 Antibody catalog # A09960. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-B3GALNT1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A09960)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human HUCE1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A09960 is reactive to B3GALNT1 in Human, Mouse, Rat

Applications

A09960 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

39512 MW

Background of B3GALNT1

Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD+/NADP+ ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase. Its substrates are however unknown.

Yazaki M., Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases.
Ishikawa K., DNA Res. 4:307-313(1997).
The MGC Project Team; Genome Res. 14:2121-2127(2004).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:2000

Validation Images & Assay Conditions

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Figure 1. Western blotting validation for Anti-B3GALNT1 Antibody A09960

Western blot analysis of extracts of various cell lines

Gene/Protein Information For B3GALNT1 (Source: Uniprot.org, NCBI)

Alternative Names

B3GALNT1; B3GALT3; b3Gal-T3; Beta-1,3-galactosyltransferase 3; Beta-1,3-GalNAc-T1; Beta-1,3-GalTase 3; beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group); beta3GalT3; Beta3Gal-T3; beta-3-Gx-T3; Brainiac1; EC 2.4.1.79; Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase; Gb4Cer ; Gb4Cer; GLCT3; Globoside Synthase; globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase; P antigen synthase; P blood group globoside; P; polypeptide 3 (Globosideblood group); UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1; UDP-GalNAc:betaGlcNAc beta 1,3-gala B3GALNT1 B3GALT3, GLCT3, GLOB, Gb4Cer, P, P1, beta3Gal-T3, galT3 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1|P antigen synthase|P blood group globoside|UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 3 (Globoside blood group)|UDP-GalNAc:betaGlcNAc beta-1,3-galactosaminyltransferase, polypeptide 1 (Globoside blood group)|UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase|b3Gal-T3|beta-1,3-GalNAc-T1|beta-1,3-GalTase 3|beta-1,3-galactosyltransferase 3|beta-3-Gx-T3|brainiac1|galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase|globoside synthase|globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase

For more info on B3GALNT1, check out the B3GALNT1 Infographic

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In this infographic, you will see the following information for B3GALNT1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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