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Product Info Summary
| SKU: | A00419 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, ICC, WB |
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Product info
Product Name
Anti-ALSFTD C9orf72 Antibody
SKU/Catalog Number
A00419
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-ALSFTD C9orf72 Antibody (Catalog # A00419). Tested in ELISA, WB, ICC applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
ALSFTD antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-ALSFTD C9orf72 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00419)
Host
Rabbit
Contents
ALSFTD Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ALSFTD antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human ALSFTD. The immunogen is located within amino acids 400 - 450 of ALSFTD.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
ALSFTD antibody is human, mouse and rat reactive. At least two isoforms are known to exist.
Reactive Species
A00419 is reactive to ALSFTD in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
54328 MW
Background of C9orf72
ALSFTD (C9orf72) is considered to play a role in gender determination (1). Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG (2). Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster (3,4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A00419 is guaranteed for ELISA, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ALSFTD antibody can be used for the detection of ALSFTD by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunocytochemistry at 10 μg/ml.
Antibody validated: Western Blot in human samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ALSFTD in HeLa cell lysate with ALSFTD antibody at 1 μg/ml.
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Immunocytochemistry of ALSFTD in A-20 cells with ALSFTD antibody at 10 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For ALSFTD (Source: Uniprot.org, NCBI)
Gene Name
ALSFTD
Full Name
Guanine nucleotide exchange C9orf72
Weight
54328 MW
Alternative Names
Amyotrophic lateral sclerosis with frontotemporal dementia, chromosome 9 open reading frame 72, C9orf72 C9orf72 ALSFTD, DENND9, DENNL72, FTDALS, FTDALS1 C9orf72-SMCR8 complex subunit guanine nucleotide exchange C9orf72|protein C9orf72
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ALSFTD, check out the ALSFTD Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ALSFTD: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-ALSFTD C9orf72 Antibody (A00419)
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No publications found for A00419
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