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- Table of Contents
Facts about Signal-regulatory protein gamma.
Engagement on T- cells by CD47 on antigen-presenting cells results in improved antigen-specific T-cell proliferation and costimulates T-cell activation. .
Human | |
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Gene Name: | SIRPG |
Uniprot: | Q9P1W8 |
Entrez: | 55423 |
Belongs to: |
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No superfamily |
bA77C3.1; CD172g antigen; CD172g; FLJ42230; signal-regulatory protein beta 2; Signal-regulatory protein beta-2; signal-regulatory protein gamma; SIRP beta 2; SIRP gamma; SIRP-B2; SIRPB2CD172 antigen-like family member B; SIRP-beta-2; SIRPG; SIRPgamma; SIRP-gamma
Mass (kDA):
42.498 kDA
Human | |
---|---|
Location: | 20p13 |
Sequence: | 20; NC_000020.11 (1629152..1686516, complement) |
Membrane; Single-pass type I membrane protein.
PMID: 11185750 by Ichigotani Y., et al. Molecular cloning of a novel human gene (SIRP-B2) which encodes a new member of the SIRP/SHPS-1 protein family.
PMID: 15383453 by Piccio L., et al. Adhesion of human T cells to antigen-presenting cells through SIRPbeta2-CD47 interaction costimulates T-cell proliferation.