Product Info Summary
SKU: | PROTQ8CC36-6 |
---|---|
Size: | 5ug,20ug,100ug |
Origin Species: | Mouse |
Source: | Escherichia coli |
Application: | Cell Culture |
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Product info
Product Name
Mouse recombinant CDNF (Cerebral dopamine neurotrophic factor) protein, AF
View all Cdnf recombinant proteins
SKU/Catalog Number
PROTQ8CC36-6
Size
5ug,20ug,100ug
Tag
His Tag (C-term)
Description
Cerebral Dopamine Neurotrophic Factor (CDNF) also known as ARMETL1, which is a member of ARMET family. Mouse CDNF shares 80% sequence identity with human CDNF. CDNF is a 20.9 kDa neurotrophic factor containing 187 residues that widely expressed in various tissues, including embryonic and postnatal brain. Besides, CDNF shows the ability to protect the degeneration of dopaminergic neurons in Parkinson's disease, induced by 6-hydroxydopamine (6-OHDA). Moreover, as a neurotrophic factor, CDNF also can repair the dopaminergic function of dopaminergic neurons.
Storage & Handling
Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months. Avoid repeated freeze/thaw cycles.
Cite This Product
Mouse recombinant CDNF (Cerebral dopamine neurotrophic factor) protein, AF (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTQ8CC36-6)
Form
Lyophilized
Formulation
The protein was lyophilized from a 0.2 μm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us.
Purity
>98% as determined by SDS-PAGE.
Predicted MW
21.032kDa
Molecular weight
The protein has a calculated MW of 19.47 kDa. The protein migrates as 17-25 kDa under reducing condition (SDS-PAGE analysis).
Activity
Testing in process
Endotoxin
<0.1 EU per 1 μg of the protein by the LAL method.
Amino Acid Sequence
MQGLEAGVGPRADCEVCKEFLDRFYNSLLSRGIDFSADTIEKELLNFCSDAKGKENRLCYYLGATTDAATKILGEVTRPMSVHIPAVKICEKLKKMDSQICELKYGKKLDLASVDLWKMRVAELKQILQRWGEECRACAEKSDYVNLIRELAPKYVEIYPQTELwith polyhistidine tag at the C-terminus.
Reconstitution
Centrifuge at 3000 rpm for 5 mins before opening. It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 100 μg/mL and incubate the stock solution at room temperature for at least 20 mins to ensure sufficient re-dissolved. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.
Assay dilution & Images
Validation Images & Assay Conditions
Click image to see more details
SDS- PAGE analysis of recombinant mouse CDNF
Protein Target Info & Infographic
Gene/Protein Information For CDNF (Source: Uniprot.org, NCBI)
Gene Name
CDNF
Full Name
Cerebral dopamine neurotrophic factor
Weight
21.032kDa
Superfamily
ARMET family
Alternative Names
ARMETL1, 9330140G23, Arme Cdnf|9330140G23, Arme, Armetl1|cerebral dopamine neurotrophic factor|cerebral dopamine neurotrophic factor|ARMET-like protein 1|arginine-rich, mutated in early stage tumors-like 1|conserved dopamine neurotrophic factor
*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".For more info on CDNF, check out the CDNF Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CDNF: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us at [email protected].
Specific Publications For Mouse recombinant CDNF (Cerebral dopamine neurotrophic factor) protein, AF (PROTQ8CC36-6)
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