IGFBP-4 Insulin-Like Growth Factor Binding Protein-4 Human

IGFBP-4 protein, Human

IGFBP-4 Human Recombinant amino acids Asp22- Glu258, produced in HEK293 cells and fused with a polyhistidine tag at the C-terminus. IGFBP4 predicted Mw is 27kDa and on SDS-PAGE appears as a 32kDa band under denaturing conditions. IGFBP4 is purified by proprietary chromatographic techniques.

Product Info Summary

SKU: PROTP22692
Size: 5ug, 20ug, 1mg
Origin Species: Human
Source: HEK293

Product Name

IGFBP-4 Insulin-Like Growth Factor Binding Protein-4 Human

View all IGFBP-4 recombinant proteins

SKU/Catalog Number

PROTP22692

Size

5ug, 20ug, 1mg

Description

IGFBP-4 Human Recombinant amino acids Asp22- Glu258, produced in HEK293 cells and fused with a polyhistidine tag at the C-terminus. IGFBP4 predicted Mw is 27kDa and on SDS-PAGE appears as a 32kDa band under denaturing conditions. IGFBP4 is purified by proprietary chromatographic techniques.

Storage & Handling

Lyophilized IGFBP4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IGFBP-4 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Cite This Product

IGFBP-4 Insulin-Like Growth Factor Binding Protein-4 Human (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTP22692)

Form

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

IGFBP 4 was lyophilized after extensive dialysis against PBS.

Purity

Greater than 95.0% as determined by SDS-PAGE.

Predicted MW

27.934kDa

Reconstitution

It is recommended to reconstitute the lyophilized IGFBP4 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Amino Acid Sequence

DEAIHCPPCS EEKLARCRPP VGCEELVREP GCGCCATCAL GLGMPCGVYT PRCGSGLRCY PPRGVEKPLH TLMHGQGVCM ELAEIEAIQE SLQPSDKDEG DHPNNSFSPC SAHDRRCLQK HFAKIRDRST SGGKMKVNGA PREDARPVPQ GSCQSELHRA LERLAASQSR THEDLYIIPI PNCDRNGNFH PKQCHPALDG QRGKCWCVDR KTGVKLPGGL EPKGELDCHQ LADSFRE + His Tag

Biological Activity

The ED50 range is 0.01-0.09µg/ml as measured by its ability to inhibit the biological activity of IGFII (20ng/ml) on MCF7 human breast adenocarcinoma cells.

Reconstitution

It is recommended to reconstitute the lyophilized IGFBP4 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Validation Images & Assay Conditions

Gene/Protein Information For IGFBP4 (Source: Uniprot.org, NCBI)

Gene Name

IGFBP4

Full Name

Insulin-like growth factor-binding protein 4

Weight

27.934kDa

Alternative Names

Insulin-like growth factor-binding protein 4; IBP-4; IGF-binding protein 4; IGFBP-4; IGFBP4; IBP4; BP-4; HT29-IGFBP IGFBP4 BP-4, HT29-IGFBP, IBP4, IGFBP-4 insulin like growth factor binding protein 4 insulin-like growth factor-binding protein 4|IBP-4|IGF-binding protein 4

*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".

For more info on IGFBP4, check out the IGFBP4 Infographic

IGFBP4 infographic

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In this infographic, you will see the following information for IGFBP4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us at [email protected].

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Size

Total: $250

SKU:PROTP22692

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