Human recombinant IL-38 (Interleukin-38) protein, AF

IL-38/IL-1F10 protein, Human

Interleukin-38 (IL-38) is a member of the interleukin-1 cytokine family. IL-38 is a ligand for soluble IL-1 receptor type I (IL-1RI). IL-38 could block the IL-36 pathway by inhibiting the IL-36 cytokine binding to their receptor. This process shows that IL-38 has anti-inflammatory properties. IL-38 is expressed in the immune organs, specifically in the skin and the tonsil, indispensable for B cell proliferation.

Product Info Summary

SKU: PROTQ8WWZ1-4
Size: 5ug,20ug,100ug
Origin Species: Human
Source: Escherichia coli
Application: Cell Culture

Product Name

Human recombinant IL-38 (Interleukin-38) protein, AF

View all IL-38/IL-1F10 recombinant proteins

SKU/Catalog Number

PROTQ8WWZ1-4

Size

5ug,20ug,100ug

Tag

His Tag (C-term)

Description

Interleukin-38 (IL-38) is a member of the interleukin-1 cytokine family. IL-38 is a ligand for soluble IL-1 receptor type I (IL-1RI). IL-38 could block the IL-36 pathway by inhibiting the IL-36 cytokine binding to their receptor. This process shows that IL-38 has anti-inflammatory properties. IL-38 is expressed in the immune organs, specifically in the skin and the tonsil, indispensable for B cell proliferation.

Storage & Handling

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months. Avoid repeated freeze/thaw cycles.

Cite This Product

Human recombinant IL-38 (Interleukin-38) protein, AF (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTQ8WWZ1-4)

Form

Lyophilized

Formulation

The protein was lyophilized from a 0.2 μm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us.

Purity

>98% as determined by SDS-PAGE.

Predicted MW

16.943kDa

Molecular weight

The protein has a calculated MW of 17.78 kDa. The protein migrates as 21 kDa under reducing condition (SDS-PAGE analysis).

Activity

Testing in process

Endotoxin

<0.1 EU per 1 μg of the protein by the LAL method.

Amino Acid Sequence

MCSLPMARYYIIKYADQKALYTRDGQLLVGDPVADNCCAEKICTLPNRGLDRTKVPIFLGIQGGSRCLACVETEEGPSLQLEDVNIEELYKGGEEATRFTFFQSSSGSAFRLEAAAWPGWFLCGPAEPQQPVQLTKESEPSARTKFYFEQSW with polyhistidine tag at the C-terminus.

Reconstitution

Centrifuge at 3000 rpm for 5 mins before opening. It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 100 μg/mL and incubate the stock solution at room temperature for at least 20 mins to ensure sufficient re-dissolved. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.

Validation Images & Assay Conditions

Gene/Protein Information For IL1F10 (Source: Uniprot.org, NCBI)

Gene Name

IL1F10

Full Name

Interleukin-1 family member 10

Weight

16.943kDa

Superfamily

IL-1 family

Alternative Names

interleukin 1 family member 10, IL1F10, FIL1-theta, FKSG75, IL-1HY2, IL1-theta, IL1HY2 IL1F10 FIL1-theta, FKSG75, IL-1HY2, IL-38, IL1-theta, IL1HY2 interleukin 1 family member 10 interleukin-1 family member 10|FIL1 theta|IL-1 theta|IL-1F10 (canonical form IL-1F10a)|family of interleukin 1-theta|interleukin 1 family member 10 (theta)|interleukin-1 HY2|interleukin-1 receptor antagonist FKSG75|interleukin-1 receptor antagonist-like FIL1 theta|interleukin-38

*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".

For more info on IL1F10, check out the IL1F10 Infographic

IL1F10 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for IL1F10: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us at [email protected].

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Size

Total: $77

SKU:PROTQ8WWZ1-4

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