Human recombinant Galectin-13 protein, AF

Galectin 13 protein, Human

Galectin-13 (Gal-13) is a lectin family member and is one of the prototype galectins. It contains one carbohydrate recognition domain (CRD), responsible for β-galactoside binding, and is biologically active as homodimers. Galectin-13 is expressed in the placenta, contributing to T cell apoptosis, immune regulation, and immune tolerance, which is indispensable for fetal development. For example, galectin-13 organizes crystal-like aggregates in the decidua, consequently attracting and killing maternal immune cells. Furthermore, galectin-13 is essential for driving neutrophil polarization in the placental-growth-permissive phenotype.

Product Info Summary

SKU: PROTQ9UHV8-2
Size: 5ug,20ug,100ug
Origin Species: Human
Source: Escherichia coli
Application: Cell Culture

Product Name

Human recombinant Galectin-13 protein, AF

View all Galectin 13 recombinant proteins

SKU/Catalog Number

PROTQ9UHV8-2

Size

5ug,20ug,100ug

Tag

His Tag (N-term)

Description

Galectin-13 (Gal-13) is a lectin family member and is one of the prototype galectins. It contains one carbohydrate recognition domain (CRD), responsible for β-galactoside binding, and is biologically active as homodimers. Galectin-13 is expressed in the placenta, contributing to T cell apoptosis, immune regulation, and immune tolerance, which is indispensable for fetal development. For example, galectin-13 organizes crystal-like aggregates in the decidua, consequently attracting and killing maternal immune cells. Furthermore, galectin-13 is essential for driving neutrophil polarization in the placental-growth-permissive phenotype.

Storage & Handling

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months. Avoid repeated freeze/thaw cycles.

Cite This Product

Human recombinant Galectin-13 protein, AF (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTQ9UHV8-2)

Form

Lyophilized

Formulation

The protein was lyophilized from a 0.2 μm filtered solution containing 1X PBS, pH 7.4. If you have any concerns or special requirements, please confirm with us.

Purity

>95% as determined by SDS-PAGE.

Predicted MW

16.119kDa

Molecular weight

The protein has a calculated MW of 16.9 kDa. The protein migrates as 17 kDa under reducing condition (SDS-PAGE analysis).

Activity

Testing in process

Endotoxin

<0.1 EU per 1 μg of the protein by the LAL method.

Amino Acid Sequence

SSLPVPYKLPVSLSVGSCVIIKGTPIHSFINDPQLQVDFYTDMDEDSDIAFRFRVHFGNHVVMNRREFGIWMLEETTDYVPFEDGKQFELCIYVHYNEYEIKVNGIRIYGFVHRIPPSFVKMVQVSRDISLTSVCVCN with polyhistidine tag at the N-terminus.

Reconstitution

Centrifuge at 3000 rpm for 5 mins before opening. It is recommended to reconstitute the lyophilized protein in sterile H₂O to a concentration not less than 100 μg/mL and incubate the stock solution at room temperature for at least 20 mins to ensure sufficient re-dissolved. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.

Validation Images & Assay Conditions

Gene/Protein Information For LGALS13 (Source: Uniprot.org, NCBI)

Gene Name

LGALS13

Full Name

Galactoside-binding soluble lectin 13

Weight

16.119kDa

Alternative Names

LGALS13, GAL13, PLAC8, PP13 LGALS13 GAL13, PLAC8, PP13 galectin 13 galactoside-binding soluble lectin 13|beta-galactoside-binding lectin|gal-13|lectin, galactoside-binding, soluble, 13|placental protein 13|placental tissue protein 13

*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".

For more info on LGALS13, check out the LGALS13 Infographic

LGALS13 infographic

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In this infographic, you will see the following information for LGALS13: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us at [email protected].

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Size

Total: $77

SKU:PROTQ9UHV8-2

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