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- Table of Contents
Facts about Alanine aminotransferase 2.
Human | |
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Gene Name: | GPT2 |
Uniprot: | Q8TD30 |
Entrez: | 84706 |
Belongs to: |
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class-I pyridoxal-phosphate-dependent aminotransferase family |
AAT2; alanine aminotransferase 2; ALT2EC 2.6.1.2; Glutamate pyruvate transaminase 2; glutamic pyruvate transaminase (alanine aminotransferase) 2; Glutamic--alanine transaminase 2; glutamic-pyruvate transaminase 2; Glutamic--pyruvic transaminase 2; GPT 2
Mass (kDA):
57.904 kDA
Human | |
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Location: | 16q11.2 |
Sequence: | 16; NC_000016.10 (46884362..46931289) |
Expressed at high levels in muscle, adipose tissue, kidney and brain and at lower levels in the liver and breast.
PMID: 11863375 by Yang R.-Z., et al. cDNA cloning, genomic structure, chromosomal mapping, and functional expression of a novel human alanine aminotransferase.
PMID: 25758935 by Celis K., et al. Loss of function mutation in glutamic pyruvate transaminase 2 (GPT2) causes developmental encephalopathy.