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FABP5 Antibodies
AND FABP5 ELISA kits, FABP5 Proteins
Many biological assays use antibodies to detect FABP5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FABP5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FABP5 antibodies...
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FABP5 Infographic by Boster Bio
All FABP5 Products
Product
Figures
Specificity
Applications
Price
Human
IHC, WB
$370
Cat # PA1475
100 μg/vial
Cat # PA1475
100 μg/vial
Mouse, Rat
IHC, WB
$370
Cat # PA1853
100 μg/vial
Cat # PA1853
100 μg/vial
Human, Mouse, Rat
IF, ICC, WB
$370
Cat # A02083
100 μg/vial
Cat # A02083
100 μg/vial
$813
Cat # PROTQ01469
20 µg
Cat # PROTQ01469
20 µg
FABP5 Overview
Facts about Fatty acid-binding protein 5.
Fatty acid-binding protein 5 (FABP5)
Intracellular carrier for long-chain fatty acids and related active lipids, like the endocannabinoid, that regulates the metabolism and activities of the ligands they bind. Along with the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they trigger nuclear receptors (PubMed:22170058).
Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta; that promotes proliferation and survival. May also function as a synaptic provider of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling.
Gene Information
| Human | |
|---|---|
| Gene Name: | FABP5 |
| Uniprot: | Q01469 |
| Entrez: | 2171 |
Family
| Belongs to: |
|---|
| calycin superfamily |
Alternative Names
EFABP; E-FABP; E-FABPPAFABP; FABP5; fatty acid binding protein 5 (psoriasis-associated); Fatty acid-binding protein 5; PA-FABPepidermal; Psoriasis-associated fatty acid-binding protein homolog
Molecular Weight
Mass (kDA):
15.164 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8q21.13 |
| Sequence: | 8; NC_000008.11 (81280536..81284775) |
Tissue Specificity
Keratinocytes; highly expressed in psoriatic skin.
Subcellular Localizations
Cytoplasm. Nucleus. Cell junction, synapse. Cell junction, synapse, postsynaptic density. Secreted. Localizes primarily to the cytoplasm. Upon certain ligand binding, a conformation change exposes a nuclear localization motif and the protein is transported into nucleus (PubMed:24692551). Secreted by astrocytes, but not by neurons (By similarity).
Diseases
- Fatty Liver
- Neoplasms
- Malignant Neoplasms
- Obesity
- Carcinoma
- Insulin Resistance
- Inflammation
- Diabetes Mellitus
- Malignant Squamous Cell Neoplasm
- Atherosclerosis
- Insulin Sensitivity
- Diabetes Mellitus, Non-insulin-dependent
- Nervousness
Pathways
- Transport
- Localization
- Cell Growth
- Lipid Binding
- Secretion
- Cell Differentiation
- Cell Proliferation
- Fatty Acid Transport
- Pathogenesis
- Cytokine Production
- Regulation Of Gene Expression
- Cellular Localization
- Immune Response
PTMs
- Phosphorylation
- Oxidation
- Acetylation
- Methylation
- Cleavage
- Carboxylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FABP5
bosterbio.com/bosterbio-gene-info-cards/FABP5
References
PMID: 1512466 by Madsen P.S., et al. Molecular cloning and expression of a novel keratinocyte protein (psoriasis-associated fatty acid-binding protein [PA-FABP]) that is highly up-regulated in psoriatic skin and that shares similarity to fatty acid-binding proteins.
PMID: 8092987 by Siegenthaler G., et al. Purification and characterization of the human epidermal fatty acid- binding protein: localization during epidermal cell differentiation in vivo and in vitro.
1 Publications of Boster FABP5 Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.wneu.2016.05.063, High FABP5 Versus CRABPII Expression Ratio in Recurrent Craniopharyngiomas: Impl...
*More publications can be found for each product on its corresponding product page