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- Table of Contents
2 Citations 6 Q&As
Facts about E3 ubiquitin-protein ligase ZNRF2.
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Human | |
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Gene Name: | ZNRF2 |
Uniprot: | Q8NHG8 |
Entrez: | 223082 |
Belongs to: |
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No superfamily |
EC 6.3.2.-; Protein Ells2; RING finger protein 202; RNF202E3 ubiquitin-protein ligase ZNRF2; zinc and ring finger 2; zinc finger/RING finger 2; Zinc/RING finger protein 2
Mass (kDA):
24.115 kDA
Human | |
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Location: | 7p14.3 |
Sequence: | 7; NC_000007.14 (30284597..30367689) |
Highly expressed in the brain, with higher expression during development than in adult. Expressed also in mammary glands, testis, colon and kidney.
Endosome membrane; Peripheral membrane protein. Lysosome membrane; Peripheral membrane protein. Cell junction, synapse, presynaptic cell membrane; Peripheral membrane protein.
PMID: 14561866 by Araki T., et al. ZNRF proteins constitute a family of presynaptic E3 ubiquitin ligases.
PMID: 16215985 by Plans V., et al. The RING finger protein RNF8 recruits UBC13 for lysine 63-based self polyubiquitylation.
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