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- Table of Contents
Facts about Zinc finger protein 408.
Human | |
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Gene Name: | ZNF408 |
Uniprot: | Q9H9D4 |
Entrez: | 79797 |
Belongs to: |
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No superfamily |
A8-51; C2-H2 type zinc finger protein; FLJ20216; HF.12; HZF3.1; KOX25zinc finger protein 3 (A8-51); PP838; Zfp113; zinc finger protein 3; Zinc finger protein HF.12; Zinc finger protein HZF3.1; Zinc finger protein KOX25
Mass (kDA):
78.439 kDA
Human | |
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Location: | 11p11.2 |
Sequence: | 11; NC_000011.10 (46701031..46705912) |
Highest expression is observed in adult retina; abundantly expressed in the fetal eye (PubMed:23716654). In the retina, it is detected in the outer nuclear layer, especially cone and rod photoreceptor cells, ganglion cell layer and both outer and inner plexiform layers (at protein level) (PubMed:25882705). Expressed in retinal blood vessels (at protein level) (PubMed:25882705).
Nucleus.
PMID: 23716654 by Collin R.W., et al. ZNF408 is mutated in familial exudative vitreoretinopathy and is crucial for the development of zebrafish retinal vasculature.
PMID: 25882705 by Avila-Fernandez A., et al. Whole-exome sequencing reveals ZNF408 as a new gene associated with autosomal recessive retinitis pigmentosa with vitreal alterations.