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ZEB1 Antibodies
AND ZEB1 ELISA kits, ZEB1 Proteins
Many biological assays use antibodies to detect ZEB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ZEB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ZEB1 antibodies...
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ZEB1 Infographic by Boster Bio
All ZEB1 Products
Product
Figures
Specificity
Applications
Price
Anti-ZEB1 Monoclonal Antibody
1 Citations 4 Q&As
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00548
100 μl
Cat # M00548
100 μl
Anti-AREB6/ZEB1 Antibody Picoband®
3 Citations 5 Q&As
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00548-2
100 μg/vial
Cat # A00548-2
100 μg/vial
Human, Mouse, Rat
IHC, WB
$523
Cat # M00548-1
100 µl
Cat # M00548-1
100 µl
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M00548-2
100 μg/vial
Cat # M00548-2
100 μg/vial
ZEB1 Overview
Facts about Zinc finger E-box-binding homeobox 1.
Zinc finger E-box-binding homeobox 1 (ZEB1)
Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression.
Enhances or represses the promoter activity of this ATP1A1 gene based on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and causes an epithelial-mesenchymal transition (EMT) by recruitment SMARCA4/BRG1.
Gene Information
| Human | |
|---|---|
| Gene Name: | ZEB1 |
| Uniprot: | P37275 |
| Entrez: | 6935 |
Family
| Belongs to: |
|---|
| delta-EF1/ZFH-1 C2H2-type zinc-finger family |
Alternative Names
AREB6; AREB6MGC133261; BZP; delta-crystallin enhancer binding factor 1; DELTAEF1; FECD6; Negative regulator of IL2; NIL-2-A zinc finger protein; NIL2A; NIL-2-A; posterior polymorphous corneal dystrophy 3; PPCD3; TCF8; TCF-8; TCF8BZP; transcription factor 8 (represses interleukin 2 expression); Transcription factor 8; ZEB; ZEB1; ZFHEP; ZFHX1A; zinc finger E-box binding homeobox 1; zinc finger E-box-binding homeobox 1; zinc finger homeodomain enhancer-binding protein
Molecular Weight
Mass (kDA):
124.074 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10p11.22 |
| Sequence: | 10; NC_000010.11 (31318417..31529814) |
Tissue Specificity
Colocalizes with SMARCA4/BRG1 in E-cadherin- negative cells from established lines, and stroma of normal colon as well as in de-differentiated epithelial cells at the invasion front of colorectal carcinomas (at protein level). Expressed in heart and skeletal muscle, but not in liver, spleen, or pancreas.
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Neoplasm Metastasis
- Cell Invasion
- Carcinoma
- Malignant Neoplasm Of Breast
- Neoplasm Invasiveness
- Mammary Neoplasms
- Tumor Progression
- Tissue Adhesions
- Cell Transformation, Neoplastic
- Malignant Paraganglionic Neoplasm
Pathways
- Epithelial To Mesenchymal Transition
- Cell Migration
- Cell Proliferation
- Pathogenesis
- Rna Interference
- Cell Cycle
- Cell Growth
- Cell Adhesion
- Methylation
- Senescence
- Drug Resistance
- Cell-cell Adhesion
- Wound Healing
PTMs
- Methylation
- Phosphorylation
- Acetylation
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ZEB1
bosterbio.com/bosterbio-gene-info-cards/ZEB1
References
PMID: 8138542 by Watanabe Y., et al. Transcription factors positively and negatively regulating the Na,K- ATPase alpha 1 subunit gene.
PMID: 1840704 by Williams T.M., et al. Identification of a zinc finger protein that inhibits IL-2 gene expression.
3 Publications of Boster ZEB1 Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.gendis.2019.12.012, All-trans retinoic acid reverses malignant biological behavior of hepatocarcinom...
- PubMed ID: 10.1016/j.bbrc.2017.12.096, MiR-181a contributes gefitinib resistance in non-small cell lung cancer cells by...
- PubMed ID: 32335297, Wang Q,Shang J,Zhang Y,Zhou Y,Tang L.MiR-451a restrains the growth and metastati...
*More publications can be found for each product on its corresponding product page