This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about GC-rich sequence DNA-binding factor 2.
Involved in pre-mRNA splicing through modulating spliceosome C complex formation. May play a role during late-stage splicing events and turnover of excised inrons.
Human | |
---|---|
Gene Name: | GCFC2 |
Uniprot: | P16383 |
Entrez: | 6936 |
Belongs to: |
---|
GCF family |
C2orf3; chromosome 2 open reading frame 3; DNABF; GC bindng factor; GCF; GCFGC binding factor; GC-rich sequence DNA-binding factor 2; GC-rich sequence DNA-binding factor; TCF9; TCF-9; transcription factor 9 (binds GC-rich sequences); Transcription factor 9
Mass (kDA):
89.385 kDA
Human | |
---|---|
Location: | 2p12 |
Sequence: | 2; NC_000002.12 (75655606..75711642, complement) |
Widely expressed in tissues and cell lines.
Nucleus, nucleoplasm. Nucleus, nucleolus.
PMID: 2556218 by Kageyama R., et al. Molecular cloning and characterization of a human DNA binding factor that represses transcription.
PMID: 17309879 by Anthoni H., et al. A locus on 2p12 containing the co-regulated MRPL19 and C2ORF3 genes is associated to dyslexia.