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- Table of Contents
Facts about YTH domain-containing family protein 1.
Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A- containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation (PubMed:26046440). .
Human | |
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Gene Name: | YTHDF1 |
Uniprot: | Q9BYJ9 |
Entrez: | 54915 |
Belongs to: |
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No superfamily |
C20orf21; DACA-1; Dermatomyositis associated with cancer putative autoantigen 1; FLJ20391; YTH domain family 1; YTH domain family protein 1; YTH domain family, member 1
Mass (kDA):
60.874 kDA
Human | |
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Location: | 20q13.33 |
Sequence: | 20; NC_000020.11 (63195429..63216131, complement) |
Cytoplasm.
PMID: 24284625 by Wang X., et al. N-methyladenosine-dependent regulation of messenger RNA stability.
PMID: 26046440 by Wang X., et al. N(6)-methyladenosine modulates messenger RNA translation efficiency.