YES1 Antibodies

AND YES1 ELISA kits, YES1 Proteins

Many biological assays use antibodies to detect YES1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with YES1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop YES1 antibodies...

We validate the specificity of these antibodies to YES1 by testing them on tissues known to express YES1 positively and negatively. Browse below to find the YES1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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YES1 Infographic by Boster Bio

All YES1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Yes1 Antibody Picoband®

3 Q&As

Human

IHC, WB

$370
Cat # PB9466
100 μg/vial

Anti-c-Yes YES1 Monoclonal Antibody

Human

ELISA, WB

$380
Cat # M02640
100ul

Anti-YES1 Antibody

Human

$299
Cat # M02640-1
50 µl

Anti-Yes1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IP, IF, IHC, ICC, WB

$370
Cat # M02640-2
100 μl/vial

YES1 (NM_005433) Human Over-expression Lysate

Human

$628
Cat # LS007525
100 µg

YES1 Overview

Facts about Tyrosine-protein kinase Yes.

YES1 3D structure. Source: alphafold

Tyrosine-protein kinase Yes (YES1)

Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, and differentiation. Stimulation by receptor tyrosine kinases (RTKs) including EGRF, PDGFR, CSF1R and FGFR contributes to recruitment of YES1 to the phosphorylated receptor, and activation and phosphorylation of downstream substrates.

Upon EGFR activation, promotes the phosphorylation of PARD3 to prefer epithelial tight junction assembly. Participates in the phosphorylation of specific junctional components such as CTNND1 by stimulating the FYN and FER tyrosine kinases in cell-cell contacts.

Gene Information

Human
Gene Name:	YES1
Uniprot:	P07947
Entrez:	7525

Family

Belongs to:

protein kinase superfamily

Alternative Names

cellular yes-1 protein; c-yes; EC 2.7.10; EC 2.7.10.2; HsT441; P61-YES; Proto-oncogene c-Yes; proto-oncogene tyrosine-protein kinase Yes; v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1; Yamaguchi sarcoma oncogene; Yes; YES1

Molecular Weight

Mass (kDA):
60.801 kDA

Genomic Context


Human

Location:	18p11.32
Sequence:	18; NC_000018.10 (721588..812846, complement)

Tissue Specificity

Expressed in the epithelial cells of renal proximal tubules and stomach as well as hematopoietic cells in the bone marrow and spleen in the fetal tissues. In adult, expressed in epithelial cells of the renal proximal tubules and present in keratinocytes in the basal epidermal layer of epidermis.

Subcellular Localizations

Cell membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytosol. Newly synthesized protein initially accumulates in the Golgi region and traffics to the plasma membrane through the exocytic pathway.