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- Table of Contents
Facts about Xenotropic and polytropic retrovirus receptor 1.
Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5- InsP7); these are important intracellular signaling molecules (PubMed:27080106). .
Human | |
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Gene Name: | XPR1 |
Uniprot: | Q9UBH6 |
Entrez: | 9213 |
Belongs to: |
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SYG1 (TC 2.A.94) family |
FLJ90308; Protein SYG1 homolog; SYG1xenotropic and polytropic retrovirus receptor; X3; Xenotropic and polytropic murine leukemia virus receptor X3; xenotropic and polytropic retrovirus receptor 1; XR; X-receptor
Mass (kDA):
81.535 kDA
Human | |
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Location: | 1q25.3 |
Sequence: | 1; NC_000001.11 (180632022..180890279) |
Widely expressed. Detected in spleen, lymph node, thymus, leukocytes, bone marrow, heart, kidney, pancreas and skeletal muscle.
Cell membrane; Multi-pass membrane protein.
PMID: 9988277 by Yang Y.-L., et al. Receptors for polytropic and xenotropic mouse leukaemia viruses encoded by a single gene at Rmc1.
PMID: 9927670 by Tailor C.S., et al. Cloning and characterization of a cell surface receptor for xenotropic and polytropic murine leukemia viruses.