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- Table of Contents
Facts about WD repeat-containing protein 74.
Required for blastocyst formation, is crucial for RNA transcription, processing and/or stability throughout preimplantation development (By similarity). .
Human | |
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Gene Name: | WDR74 |
Uniprot: | Q6RFH5 |
Entrez: | 54663 |
Belongs to: |
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No superfamily |
FLJ10439; FLJ21730; NOP seven-associated protein 1; NSA1; WD repeat domain 74; WD repeat-containing protein 74
Mass (kDA):
42.441 kDA
Human | |
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Location: | 11q12.3 |
Sequence: | 11; NC_000011.10 (62832905..62841809, complement) |
Nucleus, nucleolus. Nucleus. Nucleolar location depends on active PolI transcription of pre-rRNA.
PMID: 26456651 by Hiraishi N., et al. AAA-ATPase NVL2 acts on MTR4-exosome complex to dissociate the nucleolar protein WDR74.
PMID: 28416111 by Lo Y.H., et al. Structural Analysis Reveals Features of Ribosome Assembly Factor Nsa1/WDR74 Important for Localization and Interaction with Rix7/NVL2.