WDR18 Antibodies

AND WDR18 ELISA kits, WDR18 Proteins

Many biological assays use antibodies to detect WDR18, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with WDR18 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop WDR18 antibodies...

We validate the specificity of these antibodies to WDR18 by testing them on tissues known to express WDR18 positively and negatively. Browse below to find the WDR18 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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WDR18 Infographic by Boster Bio

All WDR18 Products

Product

Figures

Specificity

Applications

Price

Anti-WDR18 Antibody

Human, Mouse, Rat

ELISA, IHC-P, WB

$449
Cat # A13595
0.1 mg

WDR18 (NM_024100) Human Recombinant Protein

$1249
Cat # PROTQ9BV38
20 µg

WDR18 (NM_024100) Human Over-expression Lysate

Human

$628
Cat # LS057418
100 µg

WDR18 Overview

Facts about WD repeat-containing protein 18.

WDR18 3D structure. Source: alphafold

WD repeat-containing protein 18 (WDR18)

Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (PubMed:22872859). Component of the PELP1 complex involved in the nucleolar steps of 28S rRNA maturation and the subsequent nucleoplasmic transit of the pre-60S ribosomal subunit (PubMed:21326211).

Gene Information

Human
Gene Name:	WDR18
Uniprot:	Q9BV38
Entrez:	57418

Family

Belongs to:

WD repeat IPI3/WDR18 family

Alternative Names

MGC2436; R32184_1; WD repeat domain 18; WD repeat-containing protein 18

Molecular Weight

Mass (kDA):
47.405 kDA

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (982928..994557)

Subcellular Localizations

Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm. Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions.

Interacting Proteins

PELP1
SENP3
TEX10

Pathways

Ribosome Biogenesis
Eye Pigmentation
Pigmentation
Methylation
Cell Migration
Mrna Splicing
Protein Splicing
Somitogenesis
Cell Growth

Organ Morphogenesis
Localization
Nuclear Export

PTMs

Sumoylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/WDR18

References

PMID: 21326211 by Finkbeiner E., et al. The SUMO system controls nucleolar partitioning of a novel mammalian ribosome biogenesis complex.

PMID: 22872859 by Fanis P., et al. Five friends of methylated chromatin target of protein-arginine- methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation.