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- Table of Contents
Facts about Vacuolar protein sorting-associated protein 33A.
The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to modulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion likely in particular endosome subpopulations.
Rat | |
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Gene Name: | Vps33a |
Uniprot: | Q63615 |
Entrez: | 65081 |
Belongs to: |
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STXBP/unc-18/SEC1 family |
FLJ22395; FLJ23187; hVPS33A; vacuolar protein sorting 33 homolog A (S. cerevisiae); vacuolar protein sorting 33A (yeast); vacuolar protein sorting 33A; vacuolar protein sorting-associated protein 33A
Mass (kDA):
67.514 kDA
Rat | |
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Location: | 12q16 |
Sequence: | 12; |
Ubiquitous.
PMID: 8996080 by Pevsner J., et al. Mammalian homologues of yeast vacuolar protein sorting (vps) genes implicated in Golgi-to-lysosome trafficking.
PMID: 11382755 by Kim B.Y., et al. Molecular characterization of mammalian homologues of class C Vps proteins that interact with syntaxin-7.