VPS53 Antibodies

AND VPS53 ELISA kits, VPS53 Proteins

Many biological assays use antibodies to detect VPS53, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with VPS53 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop VPS53 antibodies...

We validate the specificity of these antibodies to VPS53 by testing them on tissues known to express VPS53 positively and negatively. Browse below to find the VPS53 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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VPS53 Infographic by Boster Bio

All VPS53 Products

Product

Figures

Specificity

Applications

Price

Anti-VPS53 Antibody

Human, Mouse, Rat

ELISA, IF, ICC, WB

$449
Cat # A06836
0.1 mg

VPS53 (NM_001128159) Human Recombinant Protein

$1249
Cat # PROTQ5VIR6
20 µg

Anti-VPS53 Antibody Picoband™

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A06836-1
100 μg/vial

VPS53 Overview

Facts about Vacuolar protein sorting-associated protein 53 homolog.

VPS53 3D structure. Source: alphafold

Vacuolar protein sorting-associated protein 53 homolog (VPS53)

Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545).

Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).

Gene Information

Human
Gene Name:	VPS53
Uniprot:	Q5VIR6
Entrez:	55275

Family

Belongs to:

VPS53 family

Alternative Names

FLJ10979; FLJ41112; FLJ61757; HCCS1; hVps53L; MGC39512; pp13624; vacuolar protein sorting 53 (yeast); vacuolar protein sorting 53 homolog (S. cerevisiae); vacuolar protein sorting-associated protein 53 homolog

Molecular Weight

Mass (kDA):
79.653 kDA

Genomic Context


Human

Location:	17p13.3
Sequence:	17; NC_000017.11 (508668..714846, complement)

Subcellular Localizations

Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Recycling endosome. Localizes to the trans-Golgi network as part of the GARP complex, while it localizes to recycling endosomes as part of the EARP complex (PubMed:25799061).