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Proto-oncogene vav Antibodies
AND VAV1 ELISA kits, Proto-oncogene vav Proteins
Many biological assays use antibodies to detect Proto-oncogene vav, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Proto-oncogene vav in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Proto-oncogene vav antibodies...
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VAV1 Infographic by Boster Bio
All VAV1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IF, ICC, WB
$335
Cat # A30436
100ul
Cat # A30436
100ul
Human, Mouse, Rat
ELISA
$480
Cat # EKC1589
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1589
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2009
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2009
1 kit, containing two 96-well plates and all necessary reagents
Human
IF, ICC, WB
$370
Cat # M00691Y174
100 µl/vial
Cat # M00691Y174
100 µl/vial
VAV1 Overview
Facts about Proto-oncogene vav.
Proto-oncogene vav (VAV1)
Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus resulting in cell differentiation and/or proliferation. .
Gene Information
| Human | |
|---|---|
| Gene Name: | VAV1 |
| Uniprot: | P15498 |
| Entrez: | 7409 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
oncogene vav; proto-oncogene vav; vav 1 guanine nucleotide exchange factor; vav proto-oncogene; Vav1; Vav-1; vav-T; VAVvav 1 oncogene
Molecular Weight
Mass (kDA):
98.314 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19p13.3 |
| Sequence: | 19; NC_000019.10 (6772708..6857366) |
Tissue Specificity
Widely expressed in hematopoietic cells but not in other cell types.
Diseases
- Tissue Adhesions
- Neoplasms
- Malignant Neoplasms
- Leukemia
- Cell Transformation, Neoplastic
- Lymphoma
- Immunologic Deficiency Syndromes
- Autoimmune Reaction
- Inflammation
- Autoimmunity
- Neoplasm Metastasis
- Acute Promyelocytic Leukemia
- Carcinoma
Interacting Proteins
- ABI1
- ABL1
- GAB1
- GRB2
- KHDRBS1
- LCP2
- RAC1
- SH3BP2
- ZNF655
Pathways
- Cell Activation
- T Cell Activation
- Localization
- Cell Proliferation
- Cell Development
- Cell Adhesion
- Cytokine Production
- Secretion
- Phagocytosis
- Cell Cycle
- Lymphocyte Activation
- Immune Response
- Cell Differentiation
PTMs
- Phosphorylation
- Dephosphorylation
- Methylation
- Cleavage
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/VAV1
bosterbio.com/bosterbio-gene-info-cards/VAV1
References
PMID: 2069873 by Coppola J., et al. Mechanism of activation of the vav protooncogene.
PMID: 10760587 by Denkinger D.J., et al. Genomic organization and regulation of the vav proto-oncogene.