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- Table of Contents
Facts about Guanine nucleotide exchange factor VAV2.
Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). .
Human | |
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Gene Name: | VAV2 |
Uniprot: | P52735 |
Entrez: | 7410 |
Belongs to: |
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No superfamily |
guanine nucleotide exchange factor VAV2; oncogene VAV2; Protein vav-2; vav 2 guanine nucleotide exchange factor; vav 2 oncogene; VAV-2
Mass (kDA):
101.289 kDA
Human | |
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Location: | 9q34.2 |
Sequence: | 9; NC_000009.12 (133761894..133992374, complement) |
Widely expressed.
PMID: 7762982 by Henske E.P., et al. Identification of VAV2 on 9q34 and its exclusion as the tuberous sclerosis gene TSC1.
PMID: 12454019 by Tamas P., et al. Mechanism of epidermal growth factor regulation of Vav2, a guanine nucleotide exchange factor for Rac.