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- Table of Contents
Facts about Vasorin.
Human | |
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Gene Name: | VASN |
Uniprot: | Q6EMK4 |
Entrez: | 114990 |
Belongs to: |
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No superfamily |
Atia; Protein slit-like 2; SLIT like 2; Slitl2; slit-like 2 (Drosophila); slit-like 2; VASN; Vasorin
Mass (kDA):
71.713 kDA
Human | |
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Location: | 16p13.3 |
Sequence: | 16; NC_000016.10 (4371848..4383538) |
Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells.
Membrane; Single-pass type I membrane protein. Secreted.
PMID: 15247411 by Ikeda Y., et al. Vasorin, a transforming growth factor beta-binding protein expressed in vascular smooth muscle cells, modulates the arterial response to injury in vivo.