VASH1 Antibodies

AND VASH1 ELISA kits, VASH1 Proteins

Many biological assays use antibodies to detect VASH1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with VASH1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop VASH1 antibodies...

We validate the specificity of these antibodies to VASH1 by testing them on tissues known to express VASH1 positively and negatively. Browse below to find the VASH1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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VASH1 Infographic by Boster Bio

All VASH1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-VASH1/Vasohibin Antibody

Human

$360
Cat # A04402
100 µl

Anti-Vasohibin VASH1 Antibody

13 Q&As

Human, Mouse, Rat

$399
Cat # A04402-1
100μl

Anti-VASH1 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A04402-2
0.1 mg

VASH1 (NM_014909) Human Over-expression Lysate

Human

$628
Cat # LS022846
100 µg

VASH1 Overview

Facts about Tubulinyl-Tyr carboxypeptidase 1.

VASH1 3D structure. Source: alphafold

Tubulinyl-Tyr carboxypeptidase 1 (VASH1)

Tyrosine carboxypeptidase that eliminates the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function (PubMed:29146869). Acts as an angiogenesis inhibitor: inhibits migration, proliferation and network formation by endothelial cells in addition to angiogenesis (PubMed:15467828, PubMed:16488400, PubMed:16707096, PubMed:19204325).

This inhibitory effect is selective to endothelial cells as it doesn't affect the migration of smooth muscle cells or fibroblasts (PubMed:15467828, PubMed:16488400, PubMed:16707096). .

Gene Information

Human
Gene Name:	VASH1
Uniprot:	Q7L8A9
Entrez:	22846

Family

Belongs to:

transglutaminase-like superfamily

Alternative Names

KIAA1036; KIAA1036vasohibin-1; VASH; VASH1; vasohibin 1; Vasohibin

Molecular Weight

Mass (kDA):
40.957 kDA

Genomic Context


Human

Location:	14q24.3
Sequence:	14; NC_000014.9 (76761457..76783017)

Tissue Specificity

Preferentially expressed in endothelial cells (PubMed:15467828, PubMed:16707096). Highly expressed in fetal organs (PubMed:15467828). Expressed in brain and placenta, and at lower level in heart and kidney (PubMed:15467828). Highly detected in microvessels endothelial cells of atherosclerotic lesions (PubMed:16707096).

Subcellular Localizations

Cytoplasm. Secreted. Mainly localizes in the cytoplasm (PubMed:27879017). Some fraction is secreted via a non-canonical secretion system; interaction with SVBP promotes secretion (PubMed:27879017).