UGT1A6 Antibodies

AND UGT1A6 ELISA kits, UGT1A6 Proteins

Many biological assays use antibodies to detect UGT1A6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UGT1A6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UGT1A6 antibodies...

We validate the specificity of these antibodies to UGT1A6 by testing them on tissues known to express UGT1A6 positively and negatively. Browse below to find the UGT1A6 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UGT1A6 Infographic by Boster Bio

All UGT1A6 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-UGT1A6 Antibody Picoband®

Human

ELISA, IF, ICC, WB

$370
Cat # A02239-1
100 μg/vial

Anti-UGT1A6 Antibody Picoband®

1 Q&As

Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A02239-2
100 μg/vial

Anti-UGT1A6 Antibody

Human, Mouse, Rat

$405
Cat # A02239
100ul

UGT1A6 (NM_205862) Human Recombinant Protein

$813
Cat # PROTP19224
20 µg

UGT1A6 (NM_001072) Human Over-expression Lysate

Human

$628
Cat # LS054578
100 µg

UGT1A6 Overview

Facts about UDP-glucuronosyltransferase 1-6.

UGT1A6 3D structure. Source: alphafold

UDP-glucuronosyltransferase 1-6 (UGT1A6)

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols.

Isoform 3 lacks transferase activity but acts as a negative regulator of isoform 1 (By similarity). .

Gene Information

Human
Gene Name:	UGT1A6
Uniprot:	P19224
Entrez:	54578

Family

Belongs to:

UDP-glycosyltransferase family

Alternative Names

GNT1UDPGT 1-6; HLUGP; HLUGP1; MGC29860; Phenol-metabolizing UDP-glucuronosyltransferase; UDP glucuronosyltransferase 1 family, polypeptide A6; UDP glycosyltransferase 1 family, polypeptide A6; UDP-glucuronosyltransferase 1 family polypeptide A6s; UDP-glucuronosyltransferase 1-6; UDP-glucuronosyltransferase 1A6; UDP-glucuronosyltransferase 1-F; UDPGT; UGT1; UGT1*6; UGT1.6; UGT1-06; UGT1A6S; UGT-1F; UGT1FEC 2.4.1.17

Molecular Weight

Mass (kDA):
60.751 kDA

Genomic Context


Human

Location:	2q37.1
Sequence:	2; NC_000002.12 (233691670..233773300)

Tissue Specificity

Expressed in skin. Isoforms 1 and 3 are expressed in kidney and liver. Isoform 1 but not isoform 2 is expressed in colon, esophagus and small intestine.

Subcellular Localizations

Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein.

Diseases

Malignant Neoplasms
Carcinoma
Neoplasms
Malignant Tumor Of Colon
Liver Carcinoma
Carcinogenesis
Malignant Neoplasm Of Breast
Dysequilibrium Syndrome
Liver Neoplasms, Experimental
Gilbert Disease (disorder)
Colonic Neoplasms
Adenoma
Liver Neoplasms

Hepatocarcinogenesis
Colorectal Cancer
Hyperbilirubinemia
Colorectal Neoplasms
Inflammation
Mammary Neoplasms
Adenocarcinoma

Pathways

Conjugation
Excretion
Transport
Reverse Transcription
Sulfation
Localization
Xenobiotic Glucuronidation
Intestinal Absorption
Translation
Cell Differentiation
Acyl Glucuronidation
Protein Oxidation
Membrane Assembly

Cell Cycle
Drug Transport
Metabolic Process
Cell Proliferation
Lactation
Ovulation
Bilirubin Conjugation

PTMs

Reduction
Hydroxylation
Oxidation

Phosphorylation
Deiodination
Carboxylation

Bromination

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UGT1A6

References

PMID: 1339448 by Ritter J.K., et al. A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.

PMID: 3141926 by Harding D., et al. Cloning and substrate specificity of a human phenol UDP- glucuronosyltransferase expressed in COS-7 cells.