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- Table of Contents
Facts about USP6 N-terminal-like protein.
Acts as a GTPase-activating protein for RAB5A and RAB43.
Involved in receptor trafficking.In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus.
Human | |
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Gene Name: | USP6NL |
Uniprot: | Q92738 |
Entrez: | 9712 |
Belongs to: |
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No superfamily |
KIAA0019RNTRErelated to the N terminus of tre; Related to the N-terminus of tre; RN-tre; TRE2NL; USP6 N-terminal like; USP6 N-terminal-like protein
Mass (kDA):
94.104 kDA
Human | |
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Location: | 10p14 |
Sequence: | 10; NC_000010.11 (11453946..11611789, complement) |
Widely expressed.
Golgi apparatus. Cytoplasmic vesicle.
PMID: 8700515 by Wong W.T., et al. RN-tre identifies a family of tre-related proteins displaying a novel potential protein binding domain.
PMID: 19077034 by Ishibashi K., et al. Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity.