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- Table of Contents
Facts about Ubiquitin carboxyl-terminal hydrolase 19.
Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic- reticulum-associated degradation (ERAD) substrates.
Human | |
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Gene Name: | USP19 |
Uniprot: | O94966 |
Entrez: | 10869 |
Belongs to: |
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peptidase C19 family |
Deubiquitinating enzyme 19; EC 3.1.2.15; EC 3.4.19.12; KIAA0891; Ubiquitin Carboxyl-Terminal Hydrolase 19; ubiquitin specific peptidase 19; ubiquitin thioesterase 19; Ubiquitin Thiolesterase 19; Ubiquitin-specific-processing protease 19; USP19; Zinc finger MYND domain-containing protein 9; ZMYND9; ZMYND9ubiquitin specific protease 19
Mass (kDA):
145.651 kDA
Human | |
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Location: | 3p21.31 |
Sequence: | 3; NC_000003.12 (49108046..49120938, complement) |
Endoplasmic reticulum membrane; Single-pass membrane protein.
PMID: 19465887 by Hassink G.C., et al. The ER-resident ubiquitin-specific protease 19 participates in the UPR and rescues ERAD substrates.
PMID: 21849505 by Mei Y., et al. The USP19 deubiquitinase regulates the stability of c-IAP1 and c- IAP2.