USP14 Antibodies

AND USP14 ELISA kits, USP14 Proteins

Many biological assays use antibodies to detect USP14, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with USP14 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop USP14 antibodies...

We validate the specificity of these antibodies to USP14 by testing them on tissues known to express USP14 positively and negatively. Browse below to find the USP14 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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USP14 Infographic by Boster Bio

All USP14 Products

Product

Figures

Specificity

Applications

Price

Anti-USP14 Rabbit Monoclonal Antibody

3 Q&As

Human, Mouse, Rat

Flow Cytometry, IF, ICC, WB

$370
Cat # M03042
100 μl

Anti-Usp14 Antibody

Human

Flow Cytometry, IF, IHC, ICC, WB

$405
Cat # A03042-1
100ul

Anti-UBP14 USP14 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A03042-2
100ul

USP14 (NM_005151) Human Recombinant Protein

$1249
Cat # PROTP54578
20 µg

USP14 Overview

Facts about Ubiquitin carboxyl-terminal hydrolase 14.

USP14 3D structure. Source: alphafold

Ubiquitin carboxyl-terminal hydrolase 14 (USP14)

Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin in the proteasome.

Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 that's vital for CXCL12-induced cell chemotaxis.

Gene Information

Human
Gene Name:	USP14
Uniprot:	P54578
Entrez:	9097

Family

Belongs to:

peptidase C19 family

Alternative Names

Deubiquitinating enzyme 14; EC 3.1.2.15; EC 3.4.19.12; TGT; TGTubiquitin carboxyl-terminal hydrolase 14; tRNA-guanine transglycosylase, 60-kD subunit; ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase); ubiquitin specific protease 14 (tRNA-guanine transglycosylase); Ubiquitin Thioesterase 14; Ubiquitin thiolesterase 14; ubiquitin-specific processing protease 14; Ubiquitin-specific-processing protease 14; Ubp6; USP14

Molecular Weight

Mass (kDA):
56.069 kDA

Genomic Context


Human

Location:	18p11.32
Sequence:	18; NC_000018.10 (158557..214629)

Subcellular Localizations

Cytoplasm. Cell membrane; Peripheral membrane protein.

Diseases

Ataxia
Malignant Neoplasms
Nervousness
Neoplasms
Neurodegenerative Disorders
Nervous System Disorder
Neoplasm Metastasis
Metastatic Malignant Neoplasm To The Lymph Node
Ovarian Neoplasm
Solid Tumor
Severe Acute Respiratory Syndrome
Chromosome Inversion

Tremor, Unspecified
Liver Neoplasms
Ataxia, Spinocerebellar
Leukemia, Myelocytic, Acute
Multiple Myeloma
Malignant Neoplasm Of Ovary

Interacting Proteins

PPP3CA

Pathways

Conjugation
Proteolysis
Synaptic Transmission
Localization
Pathogenesis
Aging
Dna Repair
Endocytosis
Cell Differentiation
Rna Interference
Transport
Bioluminescence
Intracellular Transport

Cell Migration
Ubiquitin Homeostasis
Nuclear Export
Spermatid Differentiation
Spermatogenesis
Dna Amplification
Chemotaxis

PTMs

Ubiquitination

Cleavage

Phosphorylation

Research Areas

Protein Turnover
Ubiquitin Proteasome Pathway

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/USP14

References

PMID: 14499622 by Reuter T.Y., et al. Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport.

PMID: 18162577 by Koulich E., et al. Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome.