USP6 Antibodies

AND USP6 ELISA kits, USP6 Proteins

Many biological assays use antibodies to detect USP6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with USP6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop USP6 antibodies...

We validate the specificity of these antibodies to USP6 by testing them on tissues known to express USP6 positively and negatively. Browse below to find the USP6 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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USP6 Infographic by Boster Bio

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Anti-UBP6 USP6 Antibody

Human

ELISA, WB

$380
Cat # A05340
100ul

USP6 Overview

Facts about Ubiquitin carboxyl-terminal hydrolase 6.

USP6 3D structure. Source: alphafold

Ubiquitin carboxyl-terminal hydrolase 6 (USP6)

Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its deubiquitination.

In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and regulates ARF6- dependent endocytic protein trafficking.

Gene Information

Human
Gene Name:	USP6
Uniprot:	P35125
Entrez:	9098

Family

Belongs to:

peptidase C19 family

Alternative Names

Deubiquitinating enzyme 6; EC 3.1.2.15; EC 3.4.19.12; HRP1; hyperpolymorphic gene 1; Proto-oncogene TRE-2; TRE17; tre-2 oncogene; Tre2; Tre-2; TRE2USP6-short; ubiquitin carboxyl-terminal hydrolase 6; ubiquitin specific peptidase 6 (Tre-2 oncogene); ubiquitin specific peptidase 6-; ubiquitin specific protease 6 (Tre-2 oncogene); ubiquitin thioesterase 6; Ubiquitin thiolesterase 6; ubiquitin-specific protease USP6; Ubiquitin-specific-processing protease 6

Molecular Weight

Mass (kDA):
158.658 kDA

Genomic Context


Human

Location:	17p13.2
Sequence:	17; NC_000017.11 (5116032..5175032)

Tissue Specificity

Testis specific. Expressed in various cancer cell lines.

Subcellular Localizations

Cell membrane. Cytoplasm. Endosome. Localizes to the plasma membrane and to filamentous structures within the cell corresponding to ARF6 regulated tubular endosomes. Activation of RAC1 and CDC42 can direct the relocalization of USP6 to the plasma membrane in a manner that depends on the integrity of the actin cytoskeleton.