UL16-binding protein 1 Antibodies

AND ULBP1 ELISA kits, UL16-binding protein 1 Proteins

Many biological assays use antibodies to detect UL16-binding protein 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UL16-binding protein 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UL16-binding protein 1 antibodies...

We validate the specificity of these antibodies to UL16-binding protein 1 by testing them on tissues known to express ULBP1 positively and negatively. Browse below to find the ULBP1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ULBP1 Infographic by Boster Bio

All ULBP1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human ULBP1 ELISA Kit PicoKine®

10 Q&As

Human

ELISA

$499
Cat # EK1685
96 wells/kit, with removable strips.

Anti-N2DL1 ULBP1 Antibody

Human

ELISA, WB

$380
Cat # A04323
100ul

Anti-ULBP1 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A04323-1
100 μg/vial

Human ULBP-1 Recombinant Protein

SDS-PAGE, Bioactivity

$251
Cat # PROTQ9BZM6
Starting from 10ug

Anti-ULBP1 Rabbit Monoclonal Antibody

Human

$370
Cat # M04323
100 μl/vial

ULBP1 Overview

Facts about UL16-binding protein 1.

ULBP1 3D structure. Source: alphafold

UL16-binding protein 1 (ULBP1)

Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. .

Gene Information

Human
Gene Name:	ULBP1
Uniprot:	Q9BZM6
Entrez:	80329

Family

Belongs to:

MHC class I family

Alternative Names

ALCAN-beta; MULT-1; N2DL1; N2DL-1; NKG2D ligand 1; NKG2DL; NKG2DL1; RAET1I; RAET1Ialcan-beta; Retinoic acid early transcript 1I; UL16 binding protein 1; UL16-binding protein 1; ULBP1; ULBP-1

Molecular Weight

Mass (kDA):
27.997 kDA

Genomic Context


Human

Location:	6q25.1
Sequence:	6; NC_000006.12 (149963943..149973715)

Tissue Specificity

Expressed in T-cells, B-cells, erythroleukemia cell lines and in a wide range of tissues including heart, brain, lung, liver, testis, lymph node, thymus, tonsil and bone marrow. Also found in fetal heart, brain, lung and liver.

Subcellular Localizations

Cell membrane; Lipid-anchor, GPI-anchor. Endoplasmic reticulum. In CMV-infected fibroblasts, detected in the endoplasmic reticulum/cis-Golgi.

Diseases

Neoplasms
Malignant Neoplasms
Cytomegalovirus Infections
Carcinoma
Leukemia
Lymphoma
Infective Disorder
Melanoma
Lung Neoplasms
Immunologic Deficiency Syndromes
Paroxysmal Nocturnal Hemoglobinuria
Ovarian Neoplasm
Adenocarcinoma

Liver Carcinoma
Malignant Paraganglionic Neoplasm
Tumor Escape
Leukemia, T-cell
Malignant Neoplasm Of Lung
Leukemia, Myelocytic, Acute
Tuberculosis

Interacting Proteins

KLRK1

Pathways

Immune Response
Cell Activation
Cytolysis
Cell Recognition
Secretion
Cell Proliferation
Chemokine Production
Cellular Senescence
Cytokine Secretion
Response To Heat
Cell Maturation
Mrna Transcription
Translation

Innate Immune Response
Antibody-dependent Cellular Cytotoxicity
Cell Killing
Glycosylation
Abscission
Localization
Glomerular Filtration

PTMs

Cleavage
Phosphorylation

Glycosylation
Gpi Anchoring

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ULBP1

References

PMID: 11239445 by Cosman D., et al. ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor.

PMID: 11827464 by Radosavljevic M., et al. A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3.