UGT1A9 Antibodies

AND UGT1A9 ELISA kits, UGT1A9 Proteins

Many biological assays use antibodies to detect UGT1A9, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UGT1A9 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UGT1A9 antibodies...

We validate the specificity of these antibodies to UGT1A9 by testing them on tissues known to express UGT1A9 positively and negatively. Browse below to find the UGT1A9 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UGT1A9 Infographic by Boster Bio

All UGT1A9 Products

Product

Figures

Specificity

Applications

Price

Anti-UGT1A9 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A01979
100ul

UGT (UGT1A9) (NM_021027) Human Over-expression Lysate

Human

$628
Cat # LS054600
100 µg

UGT1A9 Overview

Facts about UDP-glucuronosyltransferase 1-9.

UGT1A9 3D structure. Source: alphafold

UDP-glucuronosyltransferase 1-9 (UGT1A9)

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols.

Isoform 2 lacks transferase activity but functions as a negative regulator of isoform 1. .

Gene Information

Human
Gene Name:	UGT1A9
Uniprot:	O60656
Entrez:	54600

Family

Belongs to:

UDP-glycosyltransferase family

Alternative Names

A12; EC 2.4.1.17; GNT1; HLUGP4; LUGP4; polypeptide A9; UDP glucuronosyltransferase 1 family, polypeptide A9; UDP-glucuronosyltransferase 1-9; UDP-glucuronosyltransferase 1A9; UDP-glucuronosyltransferase 1-I; UDPGT 1-9; UDPGT; UDPGT1-9; UGT1; UGT1*9; UGT1.9; UGT1-09; UGT1-9; UGT1A9; UGT1AI; UGT1I; UGT-1I

Molecular Weight

Mass (kDA):
59.941 kDA

Genomic Context


Human

Location:	2q37.1
Sequence:	2; NC_000002.12 (233671898..233773300)

Tissue Specificity

Liver. Isoform 1 and isoform 2 are expressed in liver, kidney, colon, esophagus and small intestine.

Subcellular Localizations

Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Liver Carcinoma
Malignant Neoplasm Of Breast
Diarrhea
Dysequilibrium Syndrome
Colorectal Cancer
Malignant Tumor Of Colon
Liver Diseases
Hepatotoxicity
Diabetes Mellitus
Liver Neoplasms

Carcinogenesis
Cardiovascular Diseases
Hypertensive Disease
Colorectal Neoplasms
Colonic Neoplasms
Malignant Neoplasm Of Urinary Bladder
Hepatitis

Pathways

Conjugation
Excretion
Transport
Reverse Transcription
Sulfation
Acyl Glucuronidation
Intestinal Absorption
Translation
Xenobiotic Glucuronidation
Glomerular Filtration
Response To Irinotecan
Flavonoid Glucuronidation
Aging

Microtubule Depolymerization
Dna Modification
Sos Response
Cell Proliferation
Glycosylation
Localization
Bilirubin Conjugation

PTMs

Hydroxylation
Oxidation
Demethylation

Carboxylation
Glycosylation
Methylation

Deglycosylation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UGT1A9

References

PMID: 1910331 by Wooster R., et al. Cloning and stable expression of a new member of the human liver phenol/bilirubin: UDP-glucuronosyltransferase cDNA family.

PMID: 11434514 by Gong Q.H., et al. Thirteen UDP-glucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.