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- Table of Contents
Facts about UBX domain-containing protein 4.
.
Human | |
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Gene Name: | UBXN4 |
Uniprot: | Q92575 |
Entrez: | 23190 |
Belongs to: |
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No superfamily |
erasin; FLJ23318; KIAA0242KIAA2042; UBX domain containing 2; UBX domain protein 4; UBX domain-containing 1; UBX domain-containing 2; UBX domain-containing protein 2; UBX domain-containing protein 4; UBXD2; UBXDC1
Mass (kDA):
56.778 kDA
Human | |
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Location: | 2q21.3 |
Sequence: | 2; NC_000002.12 (135741855..135785056) |
Expressed in many tissues, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Accumulates in Alzheimer disease-afflicted brains (at protein level).
Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus envelope. Both the N- and the C-terminus face the cytosol. Also found in the nucleus envelope contiguous to the ER.
PMID: 16968747 by Liang J., et al. Characterization of erasin (UBXD2): a new ER protein that promotes ER-associated protein degradation.
PMID: 19822669 by Lim P.J., et al. Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD.