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- Table of Contents
Facts about Cytoplasmic FMR1-interacting protein 1.
Promotes the translation repression activity of FMR1 in mind probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia.
Mouse | |
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Gene Name: | Cyfip1 |
Uniprot: | Q7TMB8 |
Entrez: | 20430 |
Belongs to: |
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CYFIP family |
cytoplasmic FMR1 interacting protein 1; cytoplasmic FMR1-interacting protein 1; FLJ45151; KIAA0068cytoplasmic FMRP interacting protein 1; P140SRA-1; selective hybridizing clone; SHYC; Specifically Rac1-associated protein 1; SRA1; sra-1
Mass (kDA):
145.241 kDA
Mouse | |
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Location: | 7|7 B5 |
Sequence: | 7; |
Highly expressed in embryonic and adult developing nervous system.
PMID: 9756361 by Koester F., et al. Identification of shyc, a novel gene expressed in the murine developing and adult nervous system.
PMID: 14765121 by Steffen A., et al. Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation.