UBE2E1 Antibodies

AND UBE2E1 ELISA kits, UBE2E1 Proteins

Many biological assays use antibodies to detect UBE2E1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with UBE2E1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop UBE2E1 antibodies...

We validate the specificity of these antibodies to UBE2E1 by testing them on tissues known to express UBE2E1 positively and negatively. Browse below to find the UBE2E1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UBE2E1 Infographic by Boster Bio

All UBE2E1 Products

Product

Figures

Specificity

Applications

Price

UBE2E1 (NM_182666) Human Recombinant Protein

$1249
Cat # PROTP51965
20 µg

UBE2E1 (NM_182666) Human Over-expression Lysate

Human

$628
Cat # LS007324
100 µg

UBE2E1 Overview

Facts about Ubiquitin-conjugating enzyme E2 E1.

UBE2E1 3D structure. Source: alphafold

Ubiquitin-conjugating enzyme E2 E1 (UBE2E1)

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes the covalent attachment of ISG15 to other proteins.

Mediates the selective degradation of short-lived and abnormal proteins. In vitro also catalyzes 'Lys-48'-linked polyubiquitination.

Gene Information

Human
Gene Name:	UBE2E1
Uniprot:	P51965
Entrez:	7324

Family

Belongs to:

ubiquitin-conjugating enzyme family

Alternative Names

EC 6.3.2.19; UbcH6; UBE2E1; Ubiquitin carrier protein E1; ubiquitin-conjugating enzyme E2 E1; ubiquitin-conjugating enzyme E2E 1 (homologous to yeast UBC4/5); ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast); Ubiquitin-protein ligase E1

Molecular Weight

Mass (kDA):
21.404 kDA

Genomic Context


Human

Location:	3p24.2
Sequence:	3; NC_000003.12 (23805955..23891640)

Subcellular Localizations

Nucleus.

Diseases

Ataxia
Neoplasms
Lupus Erythematosus, Systemic
Autoimmune Diseases
Autoimmune Reaction
Ataxia, Spinocerebellar
Opca, Menzel Type
Neurodegenerative Disorders
Ruminant Polioencephalomalacia
Kidney Neoplasm
Malignant Neoplasm Of Lung
Rheumatism
Paraneoplastic Encephalomyelitis

Malignant Neoplasms
Sjogren's Syndrome
Acute Promyelocytic Leukemia
Cell Transformation, Neoplastic
Lung Neoplasms
Rhabdomyosarcoma
Beckwith-wiedemann Syndrome

Interacting Proteins

OTUB1
PAF1
RNF11
RNF20
RNF25

ZNRF1

Pathways

Conjugation
Transport
Methylation
Cytokine Production
Dna Repair
Proteolysis
Immune Response
Regulation Of Immune Response

Pathogenesis
Localization
Nuclear Import

PTMs

Ubiquitination
Ubiquitinylation

Methylation
Ribosylation

Research Areas

Epigenetics

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/UBE2E1

References

PMID: 8576257 by Nuber U., et al. Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2- F1) and characterization of their interaction with E6-AP and RSP5.

PMID: 16428300 by Takeuchi T., et al. Link between the ubiquitin conjugation system and the ISG15 conjugation system: ISG15 conjugation to the UbcH6 ubiquitin E2 enzyme.