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- Table of Contents
Facts about E3 ubiquitin-protein ligase TRIM9.
May act as a regulator of synaptic vesicle exocytosis by controlling the availability of SNAP25 for the SNARE complex formation. .
Mouse | |
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Gene Name: | Trim9 |
Uniprot: | Q8C7M3 |
Entrez: | 94090 |
Belongs to: |
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TRIM/RBCC family |
EC 6.3.2.-; KIAA0282homolog of rat RING finger Spring; RNF91RING finger protein 91; SPRINGE3 ubiquitin-protein ligase TRIM9; tripartite motif containing 9; tripartite motif-containing 9; Tripartite motif-containing protein 9
Mass (kDA):
90.87 kDA
Mouse | |
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Location: | 12|12 C2 |
Sequence: | 12; |
Brain. Expression is higher in the cerebral cortex and hippocampus (at protein level). Its expression is mainly confined to the central nervous system. The developing neocortex, the dorsal thalamus, the midbrain, the basal area of the hindbrain and spinal cord show high level of expression during embryogenesis. In adult brain, it is detected in the Purkinje cells of the cerebellum, in the hippocampus, and in the cortex.
PMID: 11331580 by Reymond A., et al. The tripartite motif family identifies cell compartments.
PMID: 11960705 by Berti C., et al. TRIM9 is specifically expressed in the embryonic and adult nervous system.